Primary Site >> Colorectal Cancer

Gene >> SYK

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Ref: Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).
PMID: 7657667
Ref: Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system.
PMID: 10691030
Ref: Piceatannol, a natural analog of resveratrol, inhibits progression through the S phase of the cell cycle in colorectal cancer cell lines.
PMID: 11823594
Ref: [Association between hypermethylation of Syk gene and clinicopathological characteristics in colorectal cancer patients].
PMID: 18803050
Ref: Hypermethylation and prognostic implication of Syk gene in human colorectal cancer.
PMID: 23609194
Ref: Systematic genomic identification of colorectal cancer genes delineating advanced from early clinical stage and metastasis.
PMID: 24308539
Ref: A novel and essential role for FcgammaRIIa in cancer cell-induced platelet activation.
PMID: 24258815
Ref: Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer.
PMID: 24288256
Ref: Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.
PMID: 25287946
Ref: Associations between polymorphisms in the SYK promoter and susceptibility to sporadic colorectal cancer in a Southern Han Chinese population - a short report.
PMID: 25921550
Ref: Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.
PMID: 27602108
Ref: Suppression of Spleen Tyrosine Kinase (Syk) by Histone Deacetylation Promotes, Whereas BAY61-3606, a Synthetic Syk Inhibitor Abrogates Colonocyte Apoptosis by ERK Activation.
PMID: 27293079
Ref: Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify.
PMID: 28747380
Ref: High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.
PMID: 28957395
Ref: [Spleen tyrosine kinase inhibits proliferation and promotes apoptosis of colorectal cancer cells in vitro via regulating Fra-1].
PMID: 29292261
Ref: Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
PMID: 28819788
Ref: Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
PMID: 29693170