Primary Site >> Colorectal Cancer

Gene >> SUMO1

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Ref: Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.
PMID: 11479235
Ref: Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression.
PMID: 15782138
Ref: Effect of indomethacin on cell cycle proteins in colon cancer cell lines.
PMID: 15786552
Ref: Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells.
PMID: 20525878
Ref: PIASy stimulates HIF1alpha SUMOylation and negatively regulates HIF1alpha activity in response to hypoxia.
PMID: 20661221
Ref: Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.
PMID: 23118920
Ref: Over-expression of small ubiquitin-related modifier-1 and sumoylated p53 in colon cancer.
PMID: 23640307
Ref: Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue.
PMID: 24062075
Ref: SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1.
PMID: 24775912
Ref: SUMOylated MAFB promotes colorectal cancer tumorigenesis.
PMID: 27829226
Ref: Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
PMID: 28558704
Ref: SUMOylation of IQGAP1 promotes the development of colorectal cancer.
PMID: 28987385