Primary Site >> Liver Cancer
Gene >> SULF2
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Ref: Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma. PMID: 18318435 Ref: Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets. PMID: 19086847 |
Ref: Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma. PMID: 20653060 Ref: The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation. PMID: 20725905 |
Ref: Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival. PMID: 21104785 Ref: SULFs in human neoplasia: implication as progression and prognosis factors. PMID: 21599997 Ref: The role of glypican-3 in regulating Wnt in hepatocellular carcinomas. PMID: 22563565 |
Ref: The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling. PMID: 23109092 |
Ref: Exploring the molecular causes of hepatitis B virus vaccination response: an approach with epigenomic and transcriptomic data. PMID: 24612962 |
Ref: Chemopreventive and hepatoprotective roles of adiponectin (SULF2 inhibitor) in hepatocelluar carcinoma. PMID: 26733159 Ref: SULF1/SULF2 reactivation during liver damage and tumour growth. PMID: 27013228 |
Ref: Transcriptional Induction of Periostin by a Sulfatase 2-TGFbeta1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma. PMID: 27872089 |
Ref: Targeting nitric oxide and NMDA receptor-associated pathways in treatment of high grade glial tumors. Hypotheses for nitro-memantine and nitrones. PMID: 29030124 Ref: Recapitulation of pharmacogenomic data reveals that invalidation of SULF2 enhance sorafenib susceptibility in liver cancer. PMID: 29720727 |