Primary Site >> Liver Cancer

Gene >> SULF1

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Ref: SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma.
PMID: 16762634
Ref: Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
PMID: 18318435
Ref: Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.
PMID: 19086847
Ref: Additive effect of apicidin and doxorubicin in sulfatase 1 expressing hepatocellular carcinoma in vitro and in vivo.
PMID: 19376607
Ref: Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.
PMID: 21104785
Ref: SULFs in human neoplasia: implication as progression and prognosis factors.
PMID: 21599997
Ref: HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells.
PMID: 22848304
Ref: Role of heparan sulfatases in ovarian and breast cancer.
PMID: 23359864
Ref: Activation of the transforming growth factor-beta/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma.
PMID: 25503294
Ref: Restoration of epigenetically silenced SULF1 expression by 5-aza-2-deoxycytidine sensitizes hepatocellular carcinoma cells to chemotherapy-induced apoptosis.
PMID: 26236329
Ref: SULF1/SULF2 reactivation during liver damage and tumour growth.
PMID: 27013228