Primary Site >> Colorectal Cancer

Gene >> SUFU

  • 2004
  • 2006
  • 2007
  • 2013
  • 2015
  • 2016
  • 2018
Ref: Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling.
PMID: 15077159
 Ref: WNT antagonist, SFRP1, is Hedgehog signaling target.
PMID: 16328026
Ref: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
PMID: 17089004
 Ref: Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
PMID: 17683069
 Ref: Aberrant expression of sonic hedgehog pathway in colon cancer and melanosis coli.
PMID: 23551431
 Ref: beta1 integrin mediates colorectal cancer cell proliferation and migration through regulation of the Hedgehog pathway.
PMID: 25387809
Ref: GSK3beta and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3beta downregulates the signaling pathway and reduces cell proliferation.
PMID: 26385428
 Ref: Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.
PMID: 26573582
 Ref: Itraconazole perturbs colorectal cancer dormancy through SUFU-mediated WNT inhibition.
PMID: 30250932