Primary Site >> Colorectal Cancer

Gene >> STK3

  • 2004
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  • 2016
Ref: The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
PMID: 15075335
Ref: Structural comparison of human mammalian ste20-like kinases.
PMID: 20730082
Ref: Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
PMID: 22042863
Ref: Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
PMID: 22195963
Ref: Identification of RUNX3 as a component of the MST/Hpo signaling pathway.
PMID: 21678419
Ref: The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics.
PMID: 23459937
Ref: Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.
PMID: 26370619