Primary Site >> Biliary tract Cancer

Gene >> STK11

  • 2002
  • 2003
  • 2013
  • 2014
  • 2015
  • 2016
  • 2018
Ref: Establishment and characterisation of six human biliary tract cancer cell lines.
PMID: 12107841
 Ref: Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis.
PMID: 12668978
 Ref: Pancreatic cancer risk in Peutz-Jeghers syndrome patients: a large cohort study and implications for surveillance.
PMID: 23240097
 Ref: Molecular characterization of gallbladder cancer using somatic mutation profiling.
PMID: 24508317
 Ref: Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma.
PMID: 26056085
Ref: Lovastatin overcomes gefitinib resistance through TNF-alpha signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo.
PMID: 26160843
 Ref: Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets.
PMID: 26500333
Ref: Integrin beta3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.
PMID: 26517522
Ref: Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.
PMID: 26717940
 Ref: Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy.
PMID: 30015925
Ref: The chemosensory function of primary cilia regulates cholangiocyte migration, invasion and tumor growth.
PMID: 30299561