Primary Site >> Colorectal Cancer

Gene >> ST6GAL1

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Ref: Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.
PMID: 9690558
 Ref: Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
PMID: 10673297
 Ref: Suppression of a sialyltransferase by antisense DNA reduces invasiveness of human colon cancer cells in vitro.
PMID: 11406350
Ref: Biosynthesis of the cancer-related sialyl-alpha 2,6-lactosaminyl epitope in colon cancer cell lines expressing beta-galactoside alpha 2,6-sialyltransferase under a constitutive promoter.
PMID: 11722575
 Ref: [Effect of ST6Gal I siRNA-mediated gene silencing on the adhesion and invasion of SW480 cells].
PMID: 17210104
 Ref: Protein sialylation by sialyltransferase involves radiation resistance.
PMID: 18708363
 Ref: alpha2,6-hyposialylation of c-Met abolishes cell motility of ST6Gal-I-knockdown HCT116 cells.
PMID: 19483716
 Ref: Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation.
PMID: 20127017
 Ref: Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumor.
PMID: 20167946
 Ref: Cleavage of ST6Gal I by radiation-induced BACE1 inhibits golgi-anchored ST6Gal I-mediated sialylation of integrin beta1 and migration in colon cancer cells.
PMID: 22449099
 Ref: Differential expression of ST6GAL1 in the tumor progression of colorectal cancer.
PMID: 28377225
 Ref: The glycosyltransferase ST6Gal-I is enriched in cancer stem-like cells in colorectal carcinoma and contributes to their chemo-resistance.
PMID: 29423671
Ref: Modification of alpha2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
PMID: 29981167
Ref: Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation.
PMID: 30187356