Primary Site >> Liver Cancer

Gene >> SREBF1

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Ref: Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
PMID: 17006931
 Ref: Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma.
PMID: 17484888
 Ref: Hepatitis B virus X protein induces lipogenic transcription factor SREBP1 and fatty acid synthase through the activation of nuclear receptor LXRalpha.
PMID: 18782084
 Ref: Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.
PMID: 21147110
 Ref: Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model.
PMID: 22659145
 Ref: Novel ATPase Cu(2+) transporting beta polypeptide mutations in Chinese families with Wilson's disease.
PMID: 23843956
 Ref: Kefir improves fatty liver syndrome by inhibiting the lipogenesis pathway in leptin-deficient ob/ob knockout mice.
PMID: 24335764
 Ref: Activation of ATP citrate lyase by mTOR signal induces disturbed lipid metabolism in hepatitis B virus pre-S2 mutant tumorigenesis.
PMID: 25339766
 Ref: TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway.
PMID: 28604762
Ref: Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy.
PMID: 28651018
Ref: Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice.
PMID: 29273476
 Ref: Curcumin suppress the growth of hepatocellular carcinoma via down-regulating SREBF1.
PMID: 29615146
Ref: Hepatocellular Carcinoma-Associated Protein TD26 Interacts and Enhances Sterol Regulatory Element-Binding Protein 1 Activity to Promote Tumor Cell Proliferation and Growth.
PMID: 29663480
Ref: Zhiheshouwu ethanol extract induces intrinsic apoptosis and reduces unsaturated fatty acids via SREBP1 pathway in hepatocellular carcinoma cells.
PMID: 29702135
Ref: Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.
PMID: 30004626
Ref: Bergapten inhibits liver carcinogenesis by modulating LXR/PI3K/Akt and IDOL/LDLR pathways.
PMID: 30227322