Primary Site >> Colorectal Cancer
Gene >> SREBF1
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Ref: Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia. PMID: 11082286 |
Ref: Molecular analysis of lipid-depleting factor in a colon-26-inoculated cancer cachexia model. PMID: 12209586 |
Ref: Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant crypt foci in azoxymethane-treated male rats. PMID: 16504496 Ref: Closely related colon cancer cell lines display different sensitivity to polyunsaturated fatty acids, accumulate different lipid classes and downregulate sterol regulatory element-binding protein 1. PMID: 16817902 |
Ref: The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. PMID: 22722903 |
Ref: Diacylglycerol kinase-zeta regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1. PMID: 26302180 |
Ref: The genetic basis of obesity complications. PMID: 28362475 Ref: Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy. PMID: 28651018 Ref: Expression of fatty acid synthase is regulated by PGC1alpha and contributes to increased cell proliferation. PMID: 29130104 |
Ref: Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer. PMID: 29449559 Ref: Sterol regulatory element-binding protein 1 cooperates with c-Myc to promote epithelial-mesenchymal transition in colorectal cancer. PMID: 29556313 Ref: Egg-Yolk Sphingomyelin and Phosphatidylcholine Attenuate Cholesterol Absorption in Caco-2 Cells. PMID: 29569242 |