Primary Site >> Colorectal Cancer
Gene >> SPRY2
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Ref: FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells. PMID: 16465403 |
Ref: MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. PMID: 18508928 |
Ref: SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity. PMID: 20543868 Ref: Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells. PMID: 20624167 |
Ref: Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling. PMID: 20890302 Ref: Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease. PMID: 21099344 |
Ref: MicroRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells. PMID: 22322462 |
Ref: SPROUTY2 is a beta-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. PMID: 23624922 |
Ref: Atypical role of sprouty in p21 dependent inhibition of cell proliferation in colorectal cancer. PMID: 26293890 Ref: Atypical role of sprouty in colorectal cancer: sprouty repression inhibits epithelial-mesenchymal transition. PMID: 26434583 Ref: SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. PMID: 26455323 |