Primary Site >> Stomach Cancer
Gene >> SPP1
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Ref: Co-expression of osteopontin and CD44v9 in gastric cancer. PMID: 9583725 |
Ref: [Tumor microcirculation and selective enhancement of drug delivery--clinical applications based on pathophysiological experiments]. PMID: 10945016 Ref: Molecular aspects of invasion and metastasis of stomach cancer. PMID: 11217448 |
Ref: Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays. PMID: 12127692 Ref: Appearance of osteonectin-expressing fibroblastic cells in early rat stomach carcinogenesis and stomach tumors induced with N-methyl-N'-nitro-N-nitrosoguanidine. PMID: 12359048 |
Ref: Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies. PMID: 14734468 |
Ref: [Osteopontin expression and its relation to invasion and metastases in gastric cancer]. PMID: 15946568 Ref: [Expression of osteopontin mRNA and its clinical significance in gastric cancer]. PMID: 15996323 Ref: Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors. PMID: 16048577 Ref: Metastases-related genes in the classification of liver and peritoneal metastasis in human gastric cancer. PMID: 16054651 |
Ref: [Expression of osteopontin mRNA and OCT2 mRNA in human gastric carcinoma by tissue microarray and its significance]. PMID: 16608649 Ref: [Evaluation of serum pepsinogen I , II and osteopontin co-detection in gastric cancer screening]. PMID: 17274377 |
Ref: Elevated plasma osteopontin associated with gastric cancer development, invasion and survival. PMID: 17148500 Ref: Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells. PMID: 17332338 Ref: Inhibition of osteopontin would suppress angiogenesis in gastric cancer. PMID: 17464350 Ref: The role of osteopontin in tumor progression and metastasis in breast cancer. PMID: 17548669 Ref: 213Bi-induced death of HSC45-M2 gastric cancer cells is characterized by G2 arrest and up-regulation of genes known to prevent apoptosis but induce necrosis and mitotic catastrophe. PMID: 17699730 Ref: Prognostic significance of osteopontin expression in human gastric carcinoma. PMID: 17896150 Ref: Protein expression of osteopontin in tumor tissues is an independent prognostic indicator in gastric cancer. PMID: 18004082 |
Ref: Positive correlation of osteopontin, cyclooxygenase-2 and vascular endothelial growth factor in gastric cancer. PMID: 18181047 Ref: A small interfering RNA targeting osteopontin as gastric cancer therapeutics. PMID: 18694621 Ref: Osteopontin prevents curcumin-induced apoptosis and promotes survival through Akt activation via alpha v beta 3 integrins in human gastric cancer cells. PMID: 18849546 |
Ref: Molecular basis of therapeutic approaches to gastric cancer. PMID: 19196394 Ref: Expression of osteopontin and CDX2: indications of phenotypes and prognosis in advanced gastric cancer. PMID: 19212618 Ref: Immunohistochemical expression of osteopontin in gastric cancer. PMID: 19582521 Ref: Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation. PMID: 19602039 Ref: Osteopontin expression in pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma. PMID: 19788622 |
Ref: Gene expression analysis identifies over-expression of CXCL1, SPARC, SPP1, and SULF1 in gastric cancer. PMID: 19780053 Ref: Identification and validation of genes involved in gastric tumorigenesis. PMID: 21092330 |
Ref: The function and mechanism of COX-2 in angiogenesis of gastric cancer cells. PMID: 21266034 Ref: Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells. PMID: 21286666 Ref: Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: morphometric and immunohistochemical analysis of six autopsy cases. PMID: 21450103 Ref: Increased gastric osteopontin expression by Helicobacter pylori Infection can correlate with more severe gastric inflammation and intestinal metaplasia. PMID: 21585607 |
Ref: Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers. PMID: 22912540 Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. PMID: 22929309 Ref: Genetic polymorphisms in the osteopontin promoter increases the risk of distance metastasis and death in Chinese patients with gastric cancer. PMID: 23072570 |
Ref: Canonical Wnt signaling pathway plays an essential role in N-methyl-N-nitrosurea induced gastric tumorigenesis of mice. PMID: 23117827 Ref: Osteopontin splice variants differentially exert clinicopathological features and biological functions in gastric cancer. PMID: 23289017 Ref: Osteopontin promoter polymorphisms are associated with susceptibility to gastric cancer. PMID: 23426449 Ref: Platelet-derived growth factor-A and vascular endothelial growth factor-C contribute to the development of pulmonary tumor thrombotic microangiopathy in gastric cancer. PMID: 23536282 Ref: Loss of RUNX3 increases osteopontin expression and promotes cell migration in gastric cancer. PMID: 23774402 Ref: Screening of key genes in gastric cancer with DNA microarray analysis. PMID: 24093889 |
Ref: MiR-133b is frequently decreased in gastric cancer and its overexpression reduces the metastatic potential of gastric cancer cells. PMID: 24443799 Ref: Osteopontin promotes the progression of gastric cancer through the NF-kappaB pathway regulated by the MAPK and PI3K. PMID: 24756245 Ref: Genetic association of osteopontin (OPN) and its receptor CD44 genes with susceptibility to Chinese gastric cancer patients. PMID: 25009318 Ref: RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OPN. PMID: 25172097 Ref: Serum OPN expression for identification of gastric cancer and atrophic gastritis and its influencing factors. PMID: 25479069 |
Ref: Osteopontin depletion decreases inflammation and gastric epithelial proliferation during Helicobacter pylori infection in mice. PMID: 25867766 Ref: The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progression. PMID: 25872762 Ref: A systems biology approach to detect key pathways and interaction networks in gastric cancer on the basis of microarray analysis. PMID: 26324226 Ref: Effect of BRMS1 expression on proliferation, migration and adhesion of mouse forestomach carcinoma. PMID: 26433658 Ref: Ablation of osteopontin suppresses N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric cancer development in mice. PMID: 26438603 Ref: [Expression of osteopontin splice variant and its clinical significance in gastric cancer]. PMID: 26463145 |
Ref: Osteopontin, E-cadherin, and beta-catenin expression as prognostic biomarkers in patients with radically resected gastric cancer. PMID: 25862567 Ref: Association of OPN rs11730582 polymorphism with cancer risk: a meta-analysis. PMID: 27022284 Ref: Prognostic significance of osteopontin expression in gastric cancer: a meta-analysis. PMID: 27626167 Ref: Elevated THBS2, COL1A2, and SPP1 Expression Levels as Predictors of Gastric Cancer Prognosis. PMID: 27997896 |
Ref: Signature of cytokines and angiogenic factors (CAFs) defines a clinically distinct subgroup of gastric cancer. PMID: 26681196 Ref: Prognostic implication of antitumor immunity measured by the neutrophil-lymphocyte ratio and serum cytokines and angiogenic factors in gastric cancer. PMID: 27147244 Ref: Immunohistochemical expression and localization of cytokines/chemokines/growth factors in gastric cancer. PMID: 27793525 Ref: CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer Cells. PMID: 28326306 Ref: Molecular dysexpression in gastric cancer revealed by integrated analysis of transcriptome data. PMID: 28521423 Ref: Yes, research matters. PMID: 28796840 Ref: Osteopontin -- a promising biomarker for cancer therapy. PMID: 28819419 Ref: Three-dimensional combined biomarkers assay could improve diagnostic accuracy for gastric cancer. PMID: 28912586 |
Ref: SPP1 rs4754 and its epistatic interactions with SPARC polymorphisms in gastric cancer susceptibility. PMID: 28962925 Ref: Identification of significant biomarkers and pathways associated with gastric carcinogenesis by whole genome-wide expression profiling analysis. PMID: 29328368 Ref: Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice. PMID: 29528141 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: UBE2C Is a Potential Biomarker of Intestinal-Type Gastric Cancer With Chromosomal Instability. PMID: 30116193 |