Primary Site >> Colorectal Cancer

Gene >> SPINT1

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Ref: Is intra-arterial chemotherapy worthwhile in the treatment of patients with unresectable hepatic colorectal cancer metastases?
PMID: 9038600
Ref: Evaluation of hepatocyte growth factor activator inhibitor expression in normal and malignant colonic mucosa.
PMID: 9683286
Ref: [Complete responses in patients with unresectable liver metastases from colorectal cancer with weekly high-dose 5-FU plus one-shot CDDP HAI].
PMID: 10560377
Ref: Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma.
PMID: 11085539
Ref: Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo.
PMID: 11290548
Ref: Pericellular activation of hepatocyte growth factor/scatter factor (HGF/SF) in colorectal carcinomas: roles of HGF activator (HGFA) and HGFA inhibitor type 1 (HAI-1).
PMID: 11436357
Ref: Paradoxically enhanced immunoreactivity of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in cancer cells at the invasion front.
PMID: 15471558
Ref: Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin.
PMID: 15832373
Ref: [Effect of HAI-1 over-expression on in vitro growth and migration/motility of SW620 cells].
PMID: 16044910
Ref: Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract.
PMID: 16273651
Ref: Identification of antibodies against HAI-1 and integrin alpha6beta4 as immunohistochemical markers of human villous cytotrophoblast.
PMID: 16495474
Ref: The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals.
PMID: 16820046
Ref: Treatment of multiple liver metastasis from gastric carcinoma.
PMID: 17584926
Ref: Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis.
PMID: 19555470
Ref: Imaging a functional tumorigenic biomarker in the transformed epithelium.
PMID: 23248318
Ref: Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis.
PMID: 23447577
Ref: Down-regulation of HAI-1 is associated with poor-differentiation status of colorectal cancer.
PMID: 23979832
Ref: Matrix metalloproteinase-7 induces homotypic tumor cell aggregation via proteolytic cleavage of the membrane-bound Kunitz-type inhibitor HAI-1.
PMID: 29046355
Ref: Increased expression of antisense lncRNA SPINT1-AS1 predicts a poor prognosis in colorectal cancer and is negatively correlated with its sense transcript.
PMID: 30022840