Primary Site >> Colorectal Cancer

Gene >> SPG21

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Ref: Mast cell-mediated colonic immune function and its inhibition by dietary aspirin in mice infected with Trichinella spiralis.
PMID: 7920013
Ref: Mast cell sarcoma with tissue eosinophilia arising in the ascending colon.
PMID: 10430280
Ref: Group IID heparin-binding secretory phospholipase A(2) is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues.
PMID: 12047378
Ref: Mast cells and inflammatory mediators in chronic ulcerative colitis.
PMID: 12086339
Ref: Tumour angiogenesis and mast cell density in the prognostic assessment of colorectal carcinomas.
PMID: 15888280
Ref: The association of stromal mast cell response and tumor cell differentiation in colorectal cancer.
PMID: 17718271
Ref: Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells.
PMID: 18409043
Ref: Prognostic significance of microvessel density and mast cell density for the survival of Thai patients with primary colorectal cancer.
PMID: 18672639
Ref: In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction.
PMID: 20308560
Ref: Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGD(2) metabolite, 15d-PGJ(2).
PMID: 21999315
Ref: Mast Cells in Adjacent Normal Colon Mucosa rather than Those in Invasive Margin are Related to Progression of Colon Cancer.
PMID: 23358806
Ref: Mast cells and inflammation-associated colorectal carcinogenesis.
PMID: 22993030
Ref: The expression of non-mast histamine in tumor associated microvessels in human colorectal cancers.
PMID: 23239191
Ref: IL-33 activates tumor stroma to promote intestinal polyposis.
PMID: 25918379
Ref: Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer.
PMID: 25949866
Ref: Activation of mucosal mast cells promotes inflammation-related colon cancer development through recruiting and modulating inflammatory CD11b(+)Gr1(+) cells.
PMID: 25986744
Ref: Tryptase-positive and CD117 Positive Mast Cells Correlate with Survival in Patients with Liver Metastasis.
PMID: 26408693
Ref: Mast Cell Targeted Chimeric Toxin Can Be Developed as an Adjunctive Therapy in Colon Cancer Treatment.
PMID: 26978404
Ref: The critical role of mast cell-derived hypoxia-inducible factor-1alpha in regulating mast cell function.
PMID: 27671226
Ref: A transcriptomic insight into the impacts of mast cells in lung, breast, and colon cancers.
PMID: 29147625
Ref: Orientin, a C-glycosyl dietary flavone, suppresses colonic cell proliferation and mitigates NF-kappaB mediated inflammatory response in 1,2-dimethylhydrazine induced colorectal carcinogenesis.
PMID: 29198745
Ref: Mast Cell-Dependent CD8(+) T-cell Recruitment Mediates Immune Surveillance of Intestinal Tumors in Apc(Min/+) Mice.
PMID: 29382671
Ref: Mast cells co-expressing CD68 and inorganic polyphosphate are linked with colorectal cancer.
PMID: 29543850
Ref: Low tumor infiltrating mast cell density confers prognostic benefit and reflects immunoactivation in colorectal cancer.
PMID: 29873076
Ref: Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells.
PMID: 30294327
Ref: Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models.
PMID: 30377568