Primary Site >> Colorectal Cancer

Gene >> SPDEF

  • 2009
  • 2010
  • 2011
  • 2013
  • 2014
  • 2017
Ref: PDEF is a negative regulator of colon cancer cell growth and migration.
PMID: 19830706
Ref: SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.
PMID: 19786015
Ref: Analysis of select members of the E26 (ETS) transcription factors family in colorectal cancer.
PMID: 21318373
Ref: SPDEF functions as a colorectal tumor suppressor by inhibiting beta-catenin activity.
PMID: 23376423
Ref: Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.
PMID: 25013930
Ref: SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of beta-catenin.
PMID: 28390865