Primary Site >> Colorectal Cancer

Gene >> SPATA13

  • 2007
  • 2009
  • 2013
Ref: Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element.
PMID: 17145773
Ref: Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42.
PMID: 17599059
Ref: Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.
PMID: 19151759
Ref: Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase.
PMID: 19525225
Ref: Differences in the localization of the adenomatous polyposis coli-Asef/Asef2 complex between adenomatous polyposis coli wild-type and mutant cells.
PMID: 23910005