Primary Site >> Stomach Cancer

Gene >> SPARC

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Ref: Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin-3 and BM-40/SPARC genes.
PMID: 7665251
 Ref: Appearance of osteonectin-expressing fibroblastic cells in early rat stomach carcinogenesis and stomach tumors induced with N-methyl-N'-nitro-N-nitrosoguanidine.
PMID: 12359048
 Ref: Overexpression of SPARC gene in human gastric carcinoma and its clinic-pathologic significance.
PMID: 15558074
 Ref: Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis.
PMID: 18827816
 Ref: Differential Expression of SPARC in Intestinal-type Gastric Cancer Correlates with Tumor Progression and Nodal Spread.
PMID: 19956393
 Ref: Gene expression analysis identifies over-expression of CXCL1, SPARC, SPP1, and SULF1 in gastric cancer.
PMID: 19780053
Ref: SPARC is associated with gastric cancer progression and poor survival of patients.
PMID: 20028745
Ref: Downregulation of SPARC expression decreases gastric cancer cellular invasion and survival.
PMID: 20525171
 Ref: A randomized phase 2 study of docetaxel and S-1 versus docetaxel and cisplatin in advanced gastric cancer with an evaluation of SPARC expression for personalized therapy.
PMID: 21523716
 Ref: Down-regulated SPARCL1 is associated with clinical significance in human gastric cancer.
PMID: 22161898
Ref: The role of SPARC protein expression in the progress of gastric cancer.
PMID: 22246794
Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile.
PMID: 22929309
Ref: Secreted protein acidic and rich in cysteine (SPARC) suppresses angiogenesis by down-regulating the expression of VEGF and MMP-7 in gastric cancer.
PMID: 22957090
 Ref: An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence.
PMID: 22491017
Ref: Clinical utility of measuring expression levels of KAP1, TIMP1 and STC2 in peripheral blood of patients with gastric cancer.
PMID: 23548070
Ref: Clinical significance of SPARC gene expression in patients with gastric cancer.
PMID: 24018911
 Ref: SPARC expression is negatively correlated with clinicopathological factors of gastric cancer and inhibits malignancy of gastric cancer cells.
PMID: 24676680
Ref: SPARC in Tumor Pathophysiology and as a Potential Therapeutic Target.
PMID: 24947586
Ref: Prognostic role of SPARC expression in gastric cancer: a meta-analysis.
PMID: 25395936
Ref: Aberrant methylation of the SPARC gene promoter and its clinical implication in gastric cancer.
PMID: 25516351
 Ref: Tumor profiling of gastric and esophageal carcinoma reveal different treatment options.
PMID: 25778705
Ref: Change of SPARC expression after chemotherapy in gastric cancer.
PMID: 25859409
Ref: Secreted protein acidic and rich in cysteine antagonizes bufalin-induced apoptosis in gastric cancer cells.
PMID: 25936899
Ref: CD90 is upregulated in gastric cancer tissues and inhibits gastric cancer cell apoptosis by modulating the expression level of SPARC protein.
PMID: 26329007
 Ref: Clinical Significance of "Double-hit" and "Double-protein" expression in Primary Gastric B-cell Lymphomas.
PMID: 27390596
Ref: SPARC expression in gastric cancer predicts poor prognosis: Results from a clinical cohort, pooled analysis and GSEA assay.
PMID: 28053291
 Ref: Identifying key stage-specific genes and transcription factors for gastric cancer based on RNA-sequencing data.
PMID: 28121923
Ref: Role of secreted protein acidic in hematogenous metastasis of gastric cancer.
PMID: 29077165
Ref: The relationship between stromal cell derived SPARC in human gastric cancer tissue and its clinicopathologic significance.
PMID: 29156791
 Ref: SPP1 rs4754 and its epistatic interactions with SPARC polymorphisms in gastric cancer susceptibility.
PMID: 28962925
Ref: High secreted protein acidic and rich in cysteine expression in peritumoral fibroblasts predicts better prognosis in patients with resectable gastric cancer.
PMID: 29403557
Ref: Prognostic value of gastric cancer-associated gene signatures: Evidence based on a meta-analysis using integrated bioinformatics methods.
PMID: 30133128
Ref: Expression of sushi domain containing two reflects the malignant potential of gastric cancer.
PMID: 30259711