Primary Site >> Colorectal Cancer
Gene >> SP5
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Ref: Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. PMID: 16273202 |
Ref: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. PMID: 16380080 |
Ref: Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth. PMID: 21199802 |
Ref: A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs. PMID: 22778133 |
Ref: Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice. PMID: 24552772 Ref: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. PMID: 24609463 |
Ref: Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27. PMID: 29456745 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 |