Primary Site >> Stomach Cancer
Gene >> SOX2
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Ref: Stem cells and gastric cancer: role of gastric and intestinal mixed intestinal metaplasia. PMID: 12708487 |
Ref: Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma. PMID: 14719100 |
Ref: Gastric-and-intestinal mixed-type intestinal metaplasia: aberrant expression of transcription factors and stem cell intestinalization. PMID: 16952033 |
Ref: Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression. PMID: 17136346 Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. PMID: 17611704 |
Ref: Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells. PMID: 18938748 |
Ref: Cancer stem cell-like SP cells have a high adhesion ability to the peritoneum in gastric carcinoma. PMID: 19493275 Ref: Helicobacter pylori induces gastric mucosal intestinal metaplasia through the inhibition of interleukin-4-mediated HMG box protein Sox2 expression. PMID: 19520737 |
Ref: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. PMID: 20043076 Ref: SOX2 in gastric carcinoma, but not Hath1, is related to patients' clinicopathological features and prognosis. PMID: 20532662 |
Ref: Sox2 expression is maintained while gastric phenotype is completely lost in Cdx2-induced intestinal metaplastic mucosa. PMID: 21036460 Ref: MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PMID: 21304604 Ref: Transcriptional factor typing with SOX2, HNF4aP1, and CDX2 closely relates to tumor invasion and Epstein-Barr virus status in gastric cancer. PMID: 21487519 Ref: Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer. PMID: 21996439 |
Ref: Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma. PMID: 21227461 Ref: Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line. PMID: 21913215 Ref: [Sorting of CD133(+) subset cells in human gastric cancer and the identification of their tumor initiating cell-like properties]. PMID: 22368028 Ref: miRNAs expressed differently in cancer stem cells and cancer cells of human gastric cancer cell line MKN-45. PMID: 22374783 Ref: Gastric composite tumor of alpha fetoprotein-producing carcinoma/hepatoid adenocarcinoma and endocrine carcinoma with reference to cellular phenotypes. PMID: 22482081 Ref: Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells. PMID: 22791809 Ref: Sox2 enhances the tumorigenicity and chemoresistance of cancer stem-like cells derived from gastric cancer. PMID: 23554769 |
Ref: Not all side population cells contain cancer stem-like cells in human gastric cancer cell lines. PMID: 22878917 Ref: Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties. PMID: 23229446 Ref: Characterization of cancer stem-like cells in the side population cells of human gastric cancer cell line MKN-45. PMID: 23463764 Ref: Dysregulation of CDX1, CDX2 and SOX2 in patients with gastric cancer also affects the non-malignant mucosa. PMID: 23613102 Ref: Surgical treatment for patients with Krukenberg tumor of stomach origin: clinical outcome and prognostic factors analysis. PMID: 23874550 |
Ref: RECK inhibits stemness gene expression and tumorigenicity of gastric cancer cells by suppressing ADAM-mediated Notch1 activation. PMID: 23881612 Ref: Molecular insight in gastric cancer induction: an overview of cancer stemness genes. PMID: 24078401 Ref: The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells. PMID: 24325912 Ref: Specificity protein 1 expression contributes to Bcl-w-induced aggressiveness in glioblastoma multiforme. PMID: 24552705 Ref: Autophagy promotes the survival and development of tumors by participating in the formation of vasculogenic mimicry. PMID: 24626574 Ref: SOX2 oncogenes amplified and operate to activate AKT signaling in gastric cancer and predict immunotherapy responsiveness. PMID: 24752338 Ref: Concomitant upregulation of nucleostemin and downregulation of Sox2 and Klf4 in gastric adenocarcinoma. PMID: 24763828 Ref: CDX2 can be regulated through the signalling pathways activated by IL-6 in gastric cells. PMID: 24953186 Ref: Mir-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2. PMID: 24969300 Ref: Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis. PMID: 24970812 Ref: Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome. PMID: 25300947 Ref: SOX2 as prognostic factor in head and neck cancer: a systematic review and meta-analysis. PMID: 25315908 Ref: Prognostic value of SOX2 in digestive tumors: a meta-analysis. PMID: 25436295 |
Ref: Differentiation reprogramming in gastric intestinal metaplasia and dysplasia: role of SOX2 and CDX2. PMID: 25196071 Ref: Prognostic evaluation of Nanog, Oct4, Sox2, PCNA, Ki67 and E-cadherin expression in gastric cancer. PMID: 25491144 Ref: SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN. PMID: 25543086 Ref: Stem cells in gastric cancer. PMID: 25574084 Ref: [Experimental study of human bone marrow mesenchymal stem cells on regulating the biological characteristics of gastric cancer cells]. PMID: 25656126 Ref: Downregulation of the Genes Involved in Reprogramming (SOX2, c-MYC, miR-302, miR-145, and P21) in Gastric Adenocarcinoma. PMID: 25904219 Ref: [Changes in the number of copies of genetic loci in gastric cancer]. PMID: 26299866 Ref: NKX6.3 controls gastric differentiation and tumorigenesis. PMID: 26314965 Ref: Evodiamine, a novel inhibitor of the Wnt pathway, inhibits the self-renewal of gastric cancer stem cells. PMID: 26497016 Ref: Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness. PMID: 26498753 Ref: Helicobacter pylori Eradication Reduces the Metachronous Recurrence of Gastric Neoplasms by Attenuating the Precancerous Process. PMID: 26819804 |
Ref: Hypoxic Microenvironment Induces EMT and Upgrades Stem-Like Properties of Gastric Cancer Cells. PMID: 25601854 Ref: Downregulation of lncRNA-MALAT1 Affects Proliferation and the Expression of Stemness Markers in Glioma Stem Cell Line SHG139S. PMID: 26649728 Ref: Inactivation of NKX6.3 in the stomach leads to abnormal expression of CDX2 and SOX2 required for gastric-to-intestinal transdifferentiation. PMID: 26743476 Ref: Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer. PMID: 26769843 Ref: SOX2 inhibits metastasis in gastric cancer. PMID: 26960758 Ref: PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K/Akt and p38MAPK pathways. PMID: 26968576 Ref: MicroRNA-371-5p targets SOX2 in gastric cancer. PMID: 27015119 Ref: A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth. PMID: 27107424 Ref: All-trans retinoic acid targets gastric cancer stem cells and inhibits patient-derived gastric carcinoma tumor growth. PMID: 27157616 Ref: Paradoxical role of SOX2 in gastric cancer. PMID: 27186426 Ref: Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression. PMID: 27191259 Ref: Sox2 Suppresses Gastric Tumorigenesis in Mice. PMID: 27498859 Ref: Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer. PMID: 27542229 Ref: Clinical significance of putative markers of cancer stem cells in gastric cancer: A retrospective cohort study. PMID: 27557490 Ref: [Methylation and demethylation of SOX2 gene promoter in BGC-823 gastric cancer cells]. PMID: 27596549 Ref: Long Noncoding RNA ROR Regulates Proliferation, Invasion, and Stemness of Gastric Cancer Stem Cell. PMID: 27602437 Ref: The Effect of MicroRNA-375 Overexpression, an Inhibitor of Helicobacter pylori-Induced Carcinogenesis, on lncRNA SOX2OT. PMID: 27800139 Ref: LncRNA Sox2ot overexpression serves as a poor prognostic biomarker in gastric cancer. PMID: 27904704 Ref: LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1. PMID: 28033430 |
Ref: SOX2 Inhibition Promotes Promoter Demethylation of CDX2 to Facilitate Gastric Intestinal Metaplasia. PMID: 27913994 Ref: Predictive Value of Stemness Factor Sox2 in Gastric Cancer Is Associated with Tumor Location and Stage. PMID: 28046028 Ref: IL-17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells. PMID: 28145881 Ref: HMGA2 regulates CD44 expression to promote gastric cancer cell motility and sphere formation. PMID: 28337375 Ref: Prognostic significance of KLF4 expression in gastric cancer. PMID: 28356964 Ref: USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein. PMID: 28415621 Ref: Predictive value for lymph node metastasis of epithelial-mesenchymal transition and cancer stem cell marker expression in early gastric cancer. PMID: 28595915 Ref: Clinicopathology of Early Gastric Carcinoma: An Update for Pathologists and Gastroenterologists. PMID: 28611977 Ref: The Prevalence of Cancer-Associated Autoantibodies in Patients with Gastric Cancer and Progressive Grades of Premalignant Lesions. PMID: 28768706 Ref: Metformin targets gastric cancer stem cells. PMID: 28822889 Ref: LncRNA SOX2-OT is a novel prognostic biomarker for osteosarcoma patients and regulates osteosarcoma cells proliferation and motility through modulating SOX2. PMID: 28960757 Ref: The management of localized esophageal squamous cell carcinoma: Western approach. PMID: 29129086 Ref: MiR-638 acts as a tumor suppressor gene in gastric cancer. PMID: 29296232 Ref: Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts. PMID: 29358859 |
Ref: Genome-wide expression profiling and bioinformatics analysis of deregulated genes in human gastric cancer tissue after gastroscopy. PMID: 28374495 Ref: Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin beta4/FAK/SOX2/HIF-1alpha signaling pathway in gastric cancer. PMID: 29059156 Ref: SOX2 inhibits cell proliferation and metastasis, promotes apoptotic by downregulating CCND1 and PARP in gastric cancer. PMID: 29511458 Ref: Ibuprofen reduces cell proliferation through inhibiting Wnt/beta catenin signaling pathway in gastric cancer stem cells. PMID: 29512256 Ref: Extra-capsular growth of lymph node metastasis correlates with poor prognosis and high SOX9 expression in gastric cancer. PMID: 29703178 Ref: Upregulation of bone morphogenetic protein 1 is associated with poor prognosis of late-stage gastric Cancer patients. PMID: 29720137 Ref: Isolation and identification of chemotherapy-enriched sphere-forming cells from a patient with gastric cancer. PMID: 29744869 Ref: IL-1beta promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem-like properties through PI3K pathway. PMID: 29932233 Ref: KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer. PMID: 29956735 Ref: Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis. PMID: 30147339 Ref: Retraction: MicroRNA-371-5p targets SOX2 in gastric cancer. PMID: 30197762 Ref: Differential expression of long non-coding RNA SOX2OT in Gastric Adenocarcinoma. PMID: 30198866 Ref: LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/beta-catenin pathway and predicts poor survival of glioma patients. PMID: 30208924 Ref: SOX4 contributes to TGF-beta-induced epithelial-mesenchymal transition and stem cell characteristics of gastric cancer cells. PMID: 30258935 |