Primary Site >> Colorectal Cancer

Gene >> SOX17

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Ref: Transcriptional profiling of the transition from normal intestinal epithelia to adenomas and carcinomas in the APCMin/+ mouse.
PMID: 13130079
 Ref: Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines.
PMID: 16708370
 Ref: Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells.
PMID: 17875931
 Ref: Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer.
PMID: 18413743
 Ref: Induction and down-regulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis.
PMID: 19549530
 Ref: SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma.
PMID: 20716954
 Ref: [Transcriptomic regulation and molecular mechanism of polygenic tumor at different stages].
PMID: 21873780
 Ref: Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue.
PMID: 24129635
Ref: Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas.
PMID: 24350795
 Ref: Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists.
PMID: 25432628
 Ref: The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer.
PMID: 25868860
 Ref: Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.
PMID: 26477319
Ref: Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma.
PMID: 26756304
Ref: Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer.
PMID: 27245242
Ref: 5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1.
PMID: 27513557
 Ref: The Use of Circulating Tumor DNA for Prognosis of Gastrointestinal Cancers.
PMID: 30087854
Ref: Increased expression of the thyroid hormone nuclear receptor TRalpha1 characterizes intestinal tumors with high Wnt activity.
PMID: 30123421