Primary Site >> Colorectal Cancer
Gene >> SOD2
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Ref: Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells. PMID: 1988135 |
Ref: Modifications of the anti-oxidant metabolism during proliferation and differentiation of colon tumor cell lines. PMID: 7989127 |
Ref: Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells. PMID: 9525472 Ref: Decrease of manganese superoxide dismutase activity in rats fed high levels of iron during colon carcinogenesis. PMID: 9737429 |
Ref: Dietary copper, manganese and iron affect the formation of aberrant crypts in colon of rats administered 3,2'-dimethyl-4-aminobiphenyl. PMID: 10222400 Ref: Increased growth capacity of cervical-carcinoma cells over-expressing manganous superoxide dismutase. PMID: 10360834 |
Ref: Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis. PMID: 10970696 |
Ref: The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma. PMID: 11836586 |
Ref: Significance of immunohistochemical expression of manganese superoxide dismutase as a marker of malignant potential in colorectal carcinoma. PMID: 12469142 |
Ref: MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. PMID: 15817612 Ref: Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells. PMID: 16107721 |
Ref: Complete elimination of colorectal tumor xenograft by combined manganese superoxide dismutase with tumor necrosis factor-related apoptosis-inducing ligand gene virotherapy. PMID: 16618754 Ref: Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling. PMID: 16619034 |
Ref: Combination of ZD55-MnSOD therapy with 5-FU enhances antitumor efficacy in colorectal cancer. PMID: 17632733 Ref: MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release. PMID: 17653087 |
Ref: Nuclear oxidative damage correlates with poor survival in colorectal cancer. PMID: 19066606 Ref: Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice. PMID: 19458032 Ref: Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial dysfunction. PMID: 19540247 Ref: Expression and activity of superoxide dismutase isoenzymes in colorectal cancer. PMID: 19902052 Ref: Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy. PMID: 20445800 |
Ref: PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. PMID: 20348951 Ref: Genetic variants in selenoprotein genes increase risk of colorectal cancer. PMID: 20378690 Ref: Expression of the xenobiotic- and reactive oxygen species-detoxifying enzymes, GST-pi, Cu/Zn-SOD, and Mn-SOD in the endocrine cells of colorectal cancer. PMID: 20714737 |
Ref: A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. PMID: 20644561 Ref: SOD2-mediated effects induced by WR1065 and low-dose ionizing radiation on micronucleus formation in RKO human colon carcinoma cells. PMID: 21175348 Ref: Dietary fish oil promotes colonic apoptosis and mitochondrial proton leak in oxidatively stressed mice. PMID: 21490130 Ref: [Expression of manganese superoxide dismutase in colorectal carcinoma and its relationship with clinicopathological findings]. PMID: 22509553 |
Ref: Inhibition of Tcf-4 induces apoptosis and enhances chemosensitivity of colon cancer cells. PMID: 23029137 |
Ref: A manganese superoxide dismutase (SOD2)-mediated adaptive response. PMID: 23237540 Ref: Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD. PMID: 23583431 Ref: Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell lines. PMID: 23873331 |
Ref: Association between six genetic polymorphisms and colorectal cancer: a meta-analysis. PMID: 24552298 |
Ref: Butyrate modulates antioxidant enzyme expression in malignant and non-malignant human colon tissues. PMID: 24677319 Ref: Multiple mucin depleted foci, high proliferation and low apoptotic response in the onset of colon carcinogenesis of the PIRC rat, mutated in Apc. PMID: 25257656 Ref: Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer. PMID: 25550558 Ref: Germ line polymorphisms as predictive markers for pre-surgical radiochemotherapy in locally advanced rectal cancer: a 5-year literature update and critical review. PMID: 25740678 Ref: Manganese superoxide dismutase (SOD2/MnSOD)/catalase and SOD2/GPx1 ratios as biomarkers for tumor progression and metastasis in prostate, colon, and lung cancer. PMID: 25866291 Ref: Superoxide dismutase 2 gene and cancer risk: evidence from an updated meta-analysis. PMID: 26628947 Ref: [The level of superoxide dismutase expression in primary and metastatic colorectal cancer cells in hypoxia and tissue normoxia]. PMID: 26637092 |
Ref: Superoxide-hydrogen peroxide imbalance interferes with colorectal cancer cells viability, proliferation and oxaliplatin response. PMID: 26674755 Ref: Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53. PMID: 26958937 Ref: Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells. PMID: 27470586 Ref: Immunohistochemical assessment of mitochondrial superoxide dismutase (MnSOD) in colorectal premalignant and malignant lesions. PMID: 28053678 |
Ref: Chemopreventive potential of in vitro fermented nuts in LT97 colon adenoma and primary epithelial colon cells. PMID: 27996158 Ref: Radiation-induced SOD2 overexpression sensitizes colorectal cancer to radiation while protecting normal tissue. PMID: 27999194 Ref: Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. PMID: 28414098 Ref: In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells. PMID: 29241580 Ref: Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species. PMID: 29245915 Ref: Chemopreventive Potential of Raw and Roasted Pistachios Regarding Colon Carcinogenesis. PMID: 29258268 Ref: Manganese-enhanced MRI for the detection of metastatic potential in colorectal cancer. PMID: 29708197 |
Ref: Influence of roasting on the chemopreventive potential of in vitro fermented almonds in LT97 colon adenoma cells. PMID: 28583046 Ref: Chemopreventive Potential of In Vitro Fermented Raw and Roasted Hazelnuts in LT97 Colon Adenoma Cells. PMID: 29277760 Ref: Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer. PMID: 29323702 Ref: Mechanistic Insight into Size-Dependent Enhanced Cytotoxicity of Industrial Antibacterial Titanium Oxide Nanoparticles on Colon Cells Because of Reactive Oxygen Species Quenching and Neutral Lipid Alteration. PMID: 30023799 Ref: 4-Acetyl-Antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by Inducing hsa-miR-324 re-Expression. PMID: 30103475 Ref: Non-tumor adjacent tissue of advanced stage from CRC shows activated antioxidant response. PMID: 30130568 Ref: Effects of Grape Juice in Superoxide Dismutase and Catalase in Colorectal Cancer Carcinogenesis Induced by Azoxymethane PMID: 30362310 |