Primary Site >> Stomach Cancer

Gene >> SOCS1

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Ref: Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line.
PMID: 15354212
Ref: Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma.
PMID: 15386345
Ref: Quantitative detection of methylated SOCS-1 , a tumor suppressor gene, by a modified protocol of quantitative real time methylation-specific PCR using SYBR green and its use in early gastric cancer detection.
PMID: 15483389
 Ref: Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer.
PMID: 15942635
 Ref: STAT-3 correlates with lymph node metastasis and cell survival in gastric cancer.
PMID: 21072904
 Ref: Antiproliferative effect of SOCS-1 through the suppression of STAT3 and p38 MAPK activation in gastric cancer cells.
PMID: 22095154
 Ref: miR-19a promotes cell growth and tumorigenesis through targeting SOCS1 in gastric cancer.
PMID: 23621248
Ref: A suppressor of cytokine signaling 1 antagonist enhances antigen-presenting capacity and tumor cell antigen-specific cytotoxic T lymphocyte responses by human monocyte-derived dendritic cells.
PMID: 23885028
 Ref: Uncontrolled inflammation induced by AEG-1 promotes gastric cancer and poor prognosis.
PMID: 25092897
 Ref: Gene therapy with SOCS1 for gastric cancer induces G2/M arrest and has an antitumour effect on peritoneal carcinomatosis.
PMID: 26180928
 Ref: Regulation of miR-155 affects the invasion and migration of gastric carcinoma cells by modulating the STAT3 signaling pathway.
PMID: 30250530