Primary Site >> Stomach Cancer
Gene >> SNAI2
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Ref: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. PMID: 12579345 |
Ref: Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs. PMID: 16142376 |
Ref: Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down-regulation of E-cadherin. PMID: 17299729 |
Ref: Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers. PMID: 19273255 Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 |
Ref: Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma. PMID: 20145613 Ref: Negative regulation of the tight junction protein tricellulin by snail-induced epithelial-mesenchymal transition in gastric carcinoma cells. PMID: 20332670 Ref: Helicobacter pylori potentiates epithelial:mesenchymal transition in gastric cancer: links to soluble HB-EGF, gastrin and matrix metalloproteinase-7. PMID: 20584780 |
Ref: Increased Slug and decreased E-cadherin expression is related to poor prognosis in patients with gastric cancer. PMID: 21274735 Ref: Vimentin expression is associated with decreased survival in gastric cancer. PMID: 21327330 Ref: Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers. PMID: 21898090 Ref: miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition. PMID: 22018270 |
Ref: A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression. PMID: 23059759 Ref: Smad interacting protein 1 (SIP1) is associated with peritoneal carcinomatosis in intestinal type gastric cancer. PMID: 23143680 Ref: Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/beta-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma. PMID: 23381389 |
Ref: Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition. PMID: 24070739 Ref: RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells. PMID: 24721928 Ref: CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway. PMID: 25398131 |
Ref: The miR-506-Induced Epithelial-Mesenchymal Transition is Involved in Poor Prognosis for Patients with Gastric Cancer. PMID: 25707493 Ref: Helicobacter pylori-induced epithelial-mesenchymal transition, a potential role of gastric cancer initiation and an emergence of stem cells. PMID: 25784376 Ref: Zipper-interacting protein kinase promotes epithelial-mesenchymal transition, invasion and metastasis through AKT and NF-kB signaling and is associated with metastasis and poor prognosis in gastric cancer patients. PMID: 25831050 Ref: Significances of contactin-1 expression in human gastric cancer and knockdown of contactin-1 expression inhibits invasion and metastasis of MKN45 gastric cancer cells. PMID: 25952582 Ref: BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy. PMID: 26050197 Ref: miR-203 suppression in gastric carcinoma promotes Slug-mediated cancer metastasis. PMID: 26194864 Ref: Evodiamine, a novel inhibitor of the Wnt pathway, inhibits the self-renewal of gastric cancer stem cells. PMID: 26497016 |
Ref: CCL18 promotes the invasion and migration of gastric cancer cells via ERK1/2/NF-kappaB signaling pathway. PMID: 26242263 Ref: Melatonin set out to ER stress signaling thwarts epithelial mesenchymal transition and peritoneal dissemination via calpain-mediated C/EBPbeta and NFkappaB cleavage. PMID: 26514342 Ref: STAT3 is Overactivated in Gastric Cancer Stem-Like Cells. PMID: 26862521 Ref: Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition. PMID: 26967563 Ref: MiRNA-203 suppresses tumor cell proliferation, migration and invasion by targeting Slug in gastric cancer. PMID: 27000078 Ref: ZNF143 enhances metastasis of gastric cancer by promoting the process of EMT through PI3K/AKT signaling pathway. PMID: 27449034 Ref: MicroRNA-21 promotes TGF-beta1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression. PMID: 27611950 |
Ref: REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype. PMID: 27212034 Ref: Gastrokine 1 inhibits gastric cancer cell migration and invasion by downregulating RhoA expression. PMID: 27250838 Ref: Long non-coding RNA linc00261 suppresses gastric cancer progression via promoting Slug degradation. PMID: 27878953 Ref: Liver X receptor alpha (LXRalpha) promoted invasion and EMT of gastric cancer cells by regulation of NF-kappaB activity. PMID: 28091828 Ref: Adenovirus-mediated TIPE2 overexpression inhibits gastric cancer metastasis via reversal of epithelial-mesenchymal transition. PMID: 28186089 Ref: microRNA-203 suppresses invasion of gastric cancer cells by targeting ERK1/2/Slug/ E-cadherin signaling. PMID: 28269747 Ref: MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer. PMID: 28512191 Ref: Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-beta/Smad Pathway. PMID: 28539961 Ref: Knockdown of ARK5 Expression Suppresses Invasion and Metastasis of Gastric Cancer. PMID: 28662499 Ref: Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells. PMID: 28761361 Ref: MicroRNA-124 inhibits cell invasion and epithelial-mesenchymal transition by directly repressing Snail2 in gastric cancer. PMID: 28829503 Ref: Evaluation of Slug expression is useful for predicting lymph node metastasis and survival in patients with gastric cancer. PMID: 28974196 Ref: The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer. PMID: 29069776 |
Ref: SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug-induced epithelial-mesenchymal transition. PMID: 28940639 Ref: Identification of ARL4C as a Peritoneal Dissemination-Associated Gene and Its Clinical Significance in Gastric Cancer. PMID: 29270876 Ref: DSGOST regulates resistance via activation of autophagy in gastric cancer. PMID: 29844404 Ref: Polymorphisms in TWIST1 and ZEB1 Are Associated with Prognosis of Gastric Cancer Patients. PMID: 29970507 Ref: MicroRNA-133a inhibits gastric cancer cells growth, migration, and epithelial-mesenchymal transition process by targeting presenilin 1. PMID: 30161272 Ref: P4HA3 is Epigenetically Activated by Slug in Gastric Cancer and its Deregulation is Associated With Enhanced Metastasis and Poor Survival. PMID: 30198421 |