Primary Site >> Liver Cancer
Gene >> SNAI1
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Ref: Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo. PMID: 11857019 |
Ref: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. PMID: 12579345 |
Ref: Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells. PMID: 15026811 |
Ref: Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma. PMID: 15668718 |
Ref: The transcriptional factor Snail simultaneously triggers cell cycle arrest and migration of human hepatoma HepG2. PMID: 18183498 Ref: Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma. PMID: 18691339 Ref: Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. PMID: 18801366 |
Ref: Hepatic venous pressure gradient can predict the development of hepatocellular carcinoma and hyponatremia in decompensated alcoholic cirrhosis. PMID: 19455045 Ref: High expression of Snail mRNA in blood from hepatocellular carcinoma patients with extra-hepatic metastasis. PMID: 19533388 Ref: [Hepatitis B virus X protein upregulates the transcription activity of zinc finger transcription factor SNAI1]. PMID: 19671315 Ref: Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. PMID: 19821482 |
Ref: p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma. PMID: 20385133 Ref: Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. PMID: 20564331 |
Ref: Invasion and EMT-associated genes are up-regulated in B viral hepatocellular carcinoma with high expression of CD133-human and cell culture study. PMID: 20969862 Ref: Deregulation of FoxM1b leads to tumour metastasis. PMID: 21204266 Ref: Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma. PMID: 21220499 Ref: Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma. PMID: 21480340 Ref: Clinicopathologic significance of the expression of Snail in hepatocellular carcinoma. PMID: 21494073 Ref: Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study. PMID: 21914172 Ref: Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics. PMID: 21929801 Ref: Notch1 binds and induces degradation of Snail in hepatocellular carcinoma. PMID: 22128911 Ref: [Relationship between CD44 expression or glycosylation and hepatocellular carcinoma metastasis]. PMID: 22525501 |
Ref: Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma. PMID: 22052196 Ref: Transcriptional repressor snail and metastasis in hepatocellular carcinoma. PMID: 22107747 Ref: High co-expression of vascular endothelial growth factor receptor-1 and Snail is associated with poor prognosis after curative resection of hepatocellular carcinoma. PMID: 22246525 Ref: Cyclin G1-mediated epithelial-mesenchymal transition via phosphoinositide 3-kinase/Akt signaling facilitates liver cancer progression. PMID: 22271581 Ref: Coexpression of Bcl-2 with epithelial-mesenchymal transition regulators is a prognostic indicator in hepatocellular carcinoma. PMID: 22460834 Ref: Upregulation of SATB1 promotes tumor growth and metastasis in liver cancer. PMID: 22583549 Ref: Knockdown of receptor-interacting serine/threonine protein kinase-2 (RIPK2) affects EMT-associated gene expression in human hepatoma cells. PMID: 22993319 Ref: The transcription factor GLI1 mediates TGFbeta1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism. PMID: 23185371 |
Ref: Overexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma. PMID: 22911555 Ref: The Notch1/cyclooxygenase-2/Snail/E-cadherin pathway is associated with hypoxia-induced hepatocellular carcinoma cell invasion and migration. PMID: 23124652 Ref: Reduction of fatty acid oxidation and responses to hypoxia correlate with the progression of de-differentiation in HCC. PMID: 23178736 Ref: Down-regulated KLF17 expression is associated with tumor invasion and poor prognosis in hepatocellular carcinoma. PMID: 23325444 Ref: Metastasin leads to poor prognosis of hepatocellular carcinoma through partly inducing EMT. PMID: 23483190 Ref: Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1alpha in hepatocellular carcinoma. PMID: 23496980 Ref: MicroRNA-9 enhances migration and invasion through KLF17 in hepatocellular carcinoma. PMID: 23684102 Ref: Lentivirus-delivered short hairpin RNA targeting SNAIL inhibits HepG2 cell growth. PMID: 23783653 Ref: Cell surface glycan alterations in epithelial mesenchymal transition process of Huh7 hepatocellular carcinoma cell. PMID: 23977005 Ref: Crosstalk between beta-catenin and snail in the induction of epithelial to mesenchymal transition in hepatocarcinoma: role of the ERK1/2 pathway. PMID: 24135872 |
Ref: Snail1-dependent transcriptional repression of Cezanne2 in hepatocellular carcinoma. PMID: 23792447 Ref: Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin. PMID: 24154488 Ref: BVES inhibition triggers epithelial-mesenchymal transition in human hepatocellular carcinoma. PMID: 24442236 Ref: Enhanced myeloid differentiation factor 88 promotes tumor metastasis via induction of epithelial-mesenchymal transition in human hepatocellular carcinoma. PMID: 24603331 Ref: Prostaglandin E(2) receptor EP2 mediates Snail expression in hepatocellular carcinoma cells. PMID: 24626807 Ref: HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL. PMID: 24638979 Ref: Notch1 increases Snail expression under high reactive oxygen species conditions in hepatocellular carcinoma cells. PMID: 24684482 Ref: Positive association of long telomeres with the invasive capacity of hepatocellular carcinoma cells. PMID: 24732358 Ref: Prostaglandin E2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells. PMID: 24760275 Ref: Down-regulation of Gli-1 inhibits hepatocellular carcinoma cell migration and invasion. PMID: 24792036 Ref: Effects of microRNA-30a on migration, invasion and prognosis of hepatocellular carcinoma. PMID: 24954667 Ref: Reciprocal activation between ATPase inhibitory factor 1 and NF-kappaB drives hepatocellular carcinoma angiogenesis and metastasis. PMID: 25042864 Ref: Activation of phosphatidylinositol 3-kinase/Akt signaling mediates sorafenib-induced invasion and metastasis in hepatocellular carcinoma. PMID: 25070581 Ref: Suppressed Kruppellike factor 17 expression induces tumor proliferation, metastasis and a poor prognosis in papillary thyroid carcinoma. PMID: 25109837 Ref: Protocadherin 9 inhibits epithelial-mesenchymal transition and cell migration through activating GSK-3beta in hepatocellular carcinoma. PMID: 25172662 Ref: [Serum glycoprotein profiling by lectin affinity microarray to distinguish the various stages of primary liver carcinogenesis]. PMID: 25180871 Ref: Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. PMID: 25499255 |
Ref: Decreased TIP30 promotes Snail-mediated epithelial-mesenchymal transition and tumor-initiating properties in hepatocellular carcinoma. PMID: 24681951 Ref: HAb18G/CD147 is involved in TGF-beta-induced epithelial-mesenchymal transition and hepatocellular carcinoma invasion. PMID: 25044444 Ref: Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway. PMID: 25405790 Ref: CXCR2/CXCL5 axis contributes to epithelial-mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3beta/Snail signaling. PMID: 25462858 Ref: FoxM1 overexpression promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma. PMID: 25574092 Ref: Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-kappaB pathway. PMID: 25607597 Ref: CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. PMID: 25686837 Ref: Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling. PMID: 25879771 Ref: miR-153 inhibits epithelial-to-mesenchymal transition in hepatocellular carcinoma by targeting Snail. PMID: 26035427 Ref: DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1. PMID: 26362312 |
Ref: Hepatitis C virus core protein interacts with Snail and histone deacetylases to promote the metastasis of hepatocellular carcinoma. PMID: 26549030 Ref: Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-kappaB Pathway-Mediated Epithelial-Mesenchymal Transition after Resection. PMID: 26655845 Ref: miR-192, a prognostic indicator, targets the SLC39A6/SNAIL pathway to reduce tumor metastasis in human hepatocellular carcinoma. PMID: 26684241 Ref: HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3. PMID: 26794444 Ref: Correction: Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition via Akt/GSK-3beta/snail signaling. PMID: 26901107 Ref: Epithelial-mesenchymal transition-related genes are linked to aggressive local recurrence of hepatocellular carcinoma after radiofrequency ablation. PMID: 26940140 Ref: Regulation of a TGF-beta1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells. PMID: 27041581 Ref: Suppression of epithelial-mesenchymal transition in hepatocellular carcinoma cells by Kruppel-like factor 4. PMID: 27102441 Ref: Apigenin inhibits NF-kappaB and snail signaling, EMT and metastasis in human hepatocellular carcinoma. PMID: 27203387 Ref: SNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosis. PMID: 27239445 Ref: Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells. PMID: 27725225 Ref: MicroRNA-153 inhibits tumor progression in esophageal squamous cell carcinoma by targeting SNAI1. PMID: 27739030 Ref: HSF1 promotes the inhibition of EMT-associated migration by low glucose via directly regulating Snail1 expression in HCC cells. PMID: 27755964 Ref: Inhibition of Snail Family Transcriptional Repressor 2 (SNAI2) Enhances Multidrug Resistance of Hepatocellular Carcinoma Cells. PMID: 27760172 Ref: [Expression of sal-like 4 in primary hepatocellular carcinoma and its association with epithelial-mesenchymal transition]. PMID: 27784427 |
Ref: Hepatitis C virus core protein increases Snail expression and induces epithelial-mesenchymal transition through the signal transducer and activator of transcription 3 pathway in hepatoma cells. PMID: 27381678 Ref: High expression of Snail and NF-kappaB predicts poor survival in Chinese hepatocellular carcinoma patients. PMID: 27965464 Ref: CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma. PMID: 28093067 Ref: miR-203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver. PMID: 28100026 Ref: De Novo Emergence of Mesenchymal Stem-Like CD105(+) Cancer Cells by Cytotoxic Agents in Human Hepatocellular Carcinoma. PMID: 28182993 Ref: NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-beta receptor blocker galunisertib in HCC. PMID: 28230858 Ref: Long non-coding RNA UCA1 regulates the expression of Snail2 by miR-203 to promote hepatocellular carcinoma progression. PMID: 28271214 Ref: Molecular mechanisms of 3,3'4,4',5-pentachlorobiphenyl-induced epithelial-mesenchymal transition in human hepatocellular carcinoma cells. PMID: 28284859 Ref: Downregulation of UBAP2L Inhibits the Epithelial-Mesenchymal Transition via SNAIL1 Regulation in Hepatocellular Carcinoma Cells. PMID: 28334716 Ref: High expression of G-protein signaling modulator 2 in hepatocellular carcinoma facilitates tumor growth and metastasis by activating the PI3K/AKT signaling pathway. PMID: 28347229 Ref: Fatty acid-binding protein 5 function in hepatocellular carcinoma through induction of epithelial-mesenchymal transition. PMID: 28374947 Ref: RMP promotes epithelial-mesenchymal transition through NF-kappaB/CSN2/Snail pathway in hepatocellular carcinoma. PMID: 28423737 Ref: Long noncoding RNA AWPPH promotes hepatocellular carcinoma progression through YBX1 and serves as a prognostic biomarker. PMID: 28428004 Ref: Hepatitis C virus NS4B protein induces epithelial-mesenchymal transition by upregulation of Snail. PMID: 28431572 Ref: POU2F1 over-expression correlates with poor prognoses and promotes cell growth and epithelial-to-mesenchymal transition in hepatocellular carcinoma. PMID: 28489585 Ref: Downregulated connexin32 promotes EMT through the Wnt/beta-catenin pathway by targeting Snail expression in hepatocellular carcinoma. PMID: 28498415 Ref: Propofol inhibits hepatocellular carcinoma growth and invasion through the HMGA2-mediated Wnt/beta-catenin pathway. PMID: 28565871 Ref: Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells. PMID: 28584306 Ref: MiR-155 up-regulated by TGF-beta promotes epithelial-mesenchymal transition, invasion and metastasis of human hepatocellular carcinoma cells in vitro. PMID: 28670383 Ref: GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis. PMID: 28698581 Ref: Transforming Growth Factor-beta Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail. PMID: 28734833 Ref: FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1. PMID: 28849004 Ref: Comparative Analysis for Glycopatterns and Complex-Type N-Glycans of Glycoprotein in Sera from Chronic Hepatitis B- and C-Infected Patients. PMID: 28871230 Ref: MiR-122 inhibits epithelial-mesenchymal transition in hepatocellular carcinoma by targeting Snail1 and Snail2 and suppressing WNT/beta-cadherin signaling pathway. PMID: 28890291 Ref: Mesenchymal Stem Cells Promote Hepatocarcinogenesis via lncRNA-MUF Interaction with ANXA2 and miR-34a. PMID: 28947421 Ref: Long non-coding RNA UBE2CP3 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. PMID: 29029437 Ref: miR-338-3p inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cells. PMID: 29069716 Ref: Attenuation of MET-mediated migration and invasion in hepatocellular carcinoma cells by SOCS1. PMID: 29085209 Ref: IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma. PMID: 29340101 |
Ref: Snail mediates crosstalk between TGFbeta and LXRalpha in hepatocellular carcinoma. PMID: 29230000 Ref: STAT3 aggravates TGF-beta1-induced hepatic epithelial-to-mesenchymal transition and migration. PMID: 29268242 Ref: Dihydropyrimidine dehydrogenase predicts survival and response to interferon-alpha in hepatocellular carcinoma. PMID: 29358721 Ref: Histone deacetylase inhibitors upregulate Snail via Smad2/3 phosphorylation and stabilization of Snail to promote metastasis of hepatoma cells. PMID: 29410023 Ref: STK17B promotes carcinogenesis and metastasis via AKT/GSK-3beta/Snail signaling in hepatocellular carcinoma. PMID: 29445189 Ref: NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells. PMID: 29482578 Ref: Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation. PMID: 29559743 Ref: Post-transcription mediated Snail stabilization is involved in radiation exposure induced invasion and migration of hepatocarcinoma cells. PMID: 29684855 Ref: Liver regeneration requires Yap1-TGFbeta-dependent epithelial-mesenchymal transition in hepatocytes. PMID: 29758331 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma. PMID: 29940792 Ref: The lncRNA HOTAIR transcription is controlled by HNF4alpha-induced chromatin topology modulation. PMID: 30154449 Ref: PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma. PMID: 30180906 |