Primary Site >> Stomach Cancer
Gene >> SNAI1
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Ref: Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. PMID: 12414534 |
Ref: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. PMID: 12579345 |
Ref: Neoexpression of N-cadherin in E-cadherin positive colon cancers. PMID: 15252840 |
Ref: Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs. PMID: 16142376 Ref: Epithelial-mesenchymal transition in gastric cancer (Review). PMID: 16273224 Ref: WNT2B: comparative integromics and clinical applications (Review). PMID: 16273293 |
Ref: Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down-regulation of E-cadherin. PMID: 17299729 |
Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades. PMID: 19424602 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway. PMID: 19625348 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 |
Ref: Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth. PMID: 20061081 Ref: Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma. PMID: 20145613 Ref: Negative regulation of the tight junction protein tricellulin by snail-induced epithelial-mesenchymal transition in gastric carcinoma cells. PMID: 20332670 Ref: Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells. PMID: 20637111 Ref: Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail. PMID: 20940406 |
Ref: Enhanced proliferation, invasion, and epithelial-mesenchymal transition of nicotine-promoted gastric cancer by periostin. PMID: 21677839 Ref: Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers. PMID: 21898090 Ref: Inhibition of invasion and metastasis of gastric cancer cells through snail targeting artificial microRNA interference. PMID: 22471493 |
Ref: Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer. PMID: 22018628 Ref: Snail is an independent prognostic predictor for progression and patient survival of gastric cancer. PMID: 22471696 Ref: N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition. PMID: 22844455 Ref: [Association of transcriptional repressor Snail with Lauren classification of gastric cancer]. PMID: 22941694 Ref: Prostaglandin E(2) and interleukin-1beta reduce E-cadherin expression by enhancing snail expression in gastric cancer cells. PMID: 22969242 Ref: Overexpression of Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancer. PMID: 23151184 |
Ref: Fas signaling promotes motility and metastasis through epithelial-mesenchymal transition in gastrointestinal cancer. PMID: 22508480 Ref: MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. PMID: 22614005 Ref: Smad interacting protein 1 (SIP1) is associated with peritoneal carcinomatosis in intestinal type gastric cancer. PMID: 23143680 Ref: Possible regulatory role of Snail in NF-kappaB-mediated changes in E-cadherin in gastric cancer. PMID: 23254865 Ref: A synergistic interaction between transcription factors nuclear factor-kappaB and signal transducers and activators of transcription 3 promotes gastric cancer cell migration and invasion. PMID: 23402362 Ref: COX-2 regulates E-cadherin expression through the NF-kappaB/Snail signaling pathway in gastric cancer. PMID: 23670240 Ref: MAWBP and MAWD inhibit proliferation and invasion in gastric cancer. PMID: 23687415 Ref: Bcl-w Enhances Mesenchymal Changes and Invasiveness of Glioblastoma Cells by Inducing Nuclear Accumulation of beta-Catenin. PMID: 23826359 Ref: Honokiol thwarts gastric tumor growth and peritoneal dissemination by inhibiting Tpl2 in an orthotopic model. PMID: 23828905 Ref: [CD133 promotes the invasion and metastasis of gastric cancer via epithelial-mesenchymal transition]. PMID: 23888452 Ref: [Effect of RNA interference inhibition to expression of CD133 on tumor cell biological characteristics in KATO-III CD133(+) cells of human gastric cancer]. PMID: 24062002 Ref: ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression. PMID: 24100634 Ref: Interaction between cyclooxygenase-2, Snail, and E-cadherin in gastric cancer cells. PMID: 24115825 |
Ref: EphA2 promotes epithelial-mesenchymal transition through the Wnt/beta-catenin pathway in gastric cancer cells. PMID: 23752181 Ref: Significance and prognostic value of Gli-1 and Snail/E-cadherin expression in progressive gastric cancer. PMID: 24081672 Ref: RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells. PMID: 24721928 Ref: MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression. PMID: 24736504 Ref: Gastric cancer cell growth and epithelial-mesenchymal transition are inhibited by gamma-secretase inhibitor DAPT. PMID: 24932308 Ref: microRNA-503 inhibits gastric cancer cell growth and epithelial-to-mesenchymal transition. PMID: 24944699 Ref: Epidermal growth factor-like domain-containing protein 7 (EGFL7) enhances EGF receptor-AKT signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells. PMID: 24945379 Ref: Study on the Biological Characteristics of CD133 (+) Cells Interfered by RNA Interference in Gastric Cancer. PMID: 25006468 Ref: Snail-regulated MiR-375 inhibits migration and invasion of gastric cancer cells by targeting JAK2. PMID: 25055044 Ref: Helicobacter pylori CagA promotes Snail-mediated epithelial-mesenchymal transition by reducing GSK-3 activity. PMID: 25055241 Ref: Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer. PMID: 25211665 Ref: The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination. PMID: 25226618 Ref: Thrombin conducts epithelialmesenchymal transition via proteaseactivated receptor1 in human gastric cancer. PMID: 25231630 Ref: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-beta1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-alpha-induced NF-kappa B/Snail signaling pathway in human gastric adenocarcinoma. PMID: 25370696 Ref: WAVE3 promotes epithelial-mesenchymal transition of gastric cancer through upregulation of Snail. PMID: 25378074 Ref: Combined epithelial-mesenchymal transition with cancer stem cell-like marker as predictors of recurrence after radical resection for gastric cancer. PMID: 25441488 |
Ref: Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells. PMID: 25123931 Ref: Bone morphogenetic protein 2 mediates epithelial-mesenchymal transition via AKT and ERK signaling pathways in gastric cancer. PMID: 25448881 Ref: MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-kappaB/Snail/Bcl-2 pathway. PMID: 25499851 Ref: RKIP promotes cisplatin-induced gastric cancer cell death through NF-kappaB/Snail pathway. PMID: 25547433 Ref: CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in gastric cancer. PMID: 25572817 Ref: [Experimental study of human bone marrow mesenchymal stem cells on regulating the biological characteristics of gastric cancer cells]. PMID: 25656126 Ref: MicroRNA-153 acts as a prognostic marker in gastric cancer and its role in cell migration and invasion. PMID: 25678802 Ref: Antimetastatic effects of Celastrus orbiculatus on human gastric adenocarcinoma by inhibiting epithelial-mesenchymal transition and NF-kappaB/snail signaling pathway. PMID: 25722220 Ref: Helicobacter pylori-induced epithelial-mesenchymal transition, a potential role of gastric cancer initiation and an emergence of stem cells. PMID: 25784376 Ref: Zipper-interacting protein kinase promotes epithelial-mesenchymal transition, invasion and metastasis through AKT and NF-kB signaling and is associated with metastasis and poor prognosis in gastric cancer patients. PMID: 25831050 Ref: FBXL5 inhibits metastasis of gastric cancer through suppressing Snail1. PMID: 25832584 Ref: High-mobility-group A2 overexpression provokes a poor prognosis of gastric cancer through the epithelial-mesenchymal transition. PMID: 25845850 Ref: Signal transducers and activators of transcription 3-induced metastatic potential in gastric cancer cells is enhanced by glycogen synthase kinase-3beta. PMID: 25846563 Ref: Myeloid cell leukemia-1 promotes epithelial-mesenchymal transition of human gastric cancer cells. PMID: 26058661 Ref: LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer. PMID: 26136075 Ref: Resveratrol inhibits the hedgehog signaling pathway and epithelial-mesenchymal transition and suppresses gastric cancer invasion and metastasis. PMID: 26137075 Ref: MiR-153 regulates metastases of gastric cancer through Snail. PMID: 26232914 Ref: miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer. PMID: 26264654 Ref: Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer. PMID: 26373288 Ref: MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail. PMID: 26610210 Ref: GM130 regulates epithelial-to-mesenchymal transition and invasion of gastric cancer cells via snail. PMID: 26617790 Ref: CXCL1 expression is correlated with Snail expression and affects the prognosis of patients with gastric cancer. PMID: 26622871 |
Ref: Hypoxic Microenvironment Induces EMT and Upgrades Stem-Like Properties of Gastric Cancer Cells. PMID: 25601854 Ref: Fbxw7 regulates tumor apoptosis, growth arrest and the epithelial-to-mesenchymal transition in part through the RhoA signaling pathway in gastric cancer. PMID: 26458995 Ref: Melatonin set out to ER stress signaling thwarts epithelial mesenchymal transition and peritoneal dissemination via calpain-mediated C/EBPbeta and NFkappaB cleavage. PMID: 26514342 Ref: Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. PMID: 26716415 Ref: miR-204 regulates the EMT by targeting snai1 to suppress the invasion and migration of gastric cancer. PMID: 26729198 Ref: Helicobacter pylori induces Snail expression through ROS-mediated activation of Erk and inactivation of GSK-3beta in human gastric cancer cells. PMID: 26808296 Ref: Cisplatin resistance in gastric cancer cells is associated with HER2 upregulation-induced epithelial-mesenchymal transition. PMID: 26846307 Ref: C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits. PMID: 26855187 Ref: Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways. PMID: 26859571 Ref: Resistin-Like Molecule-beta Promotes Invasion and Migration of Gastric Carcinoma Cells. PMID: 27001185 Ref: Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma. PMID: 27058427 Ref: FOXQ1 promotes gastric cancer metastasis through upregulation of Snail. PMID: 27109028 Ref: DDR1 enhances invasion and metastasis of gastric cancer via epithelial-mesenchymal transition. PMID: 27179963 Ref: MiR-30a increases cisplatin sensitivity of gastric cancer cells through suppressing epithelial-to-mesenchymal transition (EMT). PMID: 27212164 Ref: Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis. PMID: 27279633 Ref: Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3beta signaling in gastric cancer. PMID: 27323966 Ref: URI promotes gastric cancer cell motility, survival, and resistance to adriamycin in vitro. PMID: 27429854 Ref: ZNF143 enhances metastasis of gastric cancer by promoting the process of EMT through PI3K/AKT signaling pathway. PMID: 27449034 Ref: The clinical significance of snail protein expression in gastric cancer: a meta-analysis. PMID: 27461247 Ref: Helicobacter pylori CagA and IL-1beta Promote the Epithelial-to-Mesenchymal Transition in a Nontransformed Epithelial Cell Model. PMID: 27525003 Ref: MiR-203 inhibits tumor invasion and metastasis in gastric cancer by ATM. PMID: 27542403 Ref: Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice. PMID: 27569891 Ref: ADAM17 promotes epithelial-mesenchymal transition via TGF-beta/Smad pathway in gastric carcinoma cells. PMID: 27779657 Ref: Knockdown of Radixin Suppresses Gastric Cancer Metastasis In Vitro by Up-Regulation of E-Cadherin via NF-kappaB/Snail Pathway. PMID: 27855404 Ref: Identification of aberrantly expressed glycans in gastric cancer by integrated lectin microarray and mass spectrometric analyses. PMID: 27895315 |
Ref: REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype. PMID: 27212034 Ref: Gastrokine 1 inhibits gastric cancer cell migration and invasion by downregulating RhoA expression. PMID: 27250838 Ref: HIF-1alpha induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway. PMID: 28076840 Ref: MALAT1 promoted invasiveness of gastric adenocarcinoma. PMID: 28077118 Ref: Liver X receptor alpha (LXRalpha) promoted invasion and EMT of gastric cancer cells by regulation of NF-kappaB activity. PMID: 28091828 Ref: Role of miR-647 in human gastric cancer suppression. PMID: 28098914 Ref: Adenovirus-mediated TIPE2 overexpression inhibits gastric cancer metastasis via reversal of epithelial-mesenchymal transition. PMID: 28186089 Ref: CCL2 expression correlates with Snail expression and affects the prognosis of patients with gastric cancer. PMID: 28215642 Ref: Clinical significance of altering epithelial-mesenchymal transition in metastatic lymph nodes of gastric cancer. PMID: 28247164 Ref: Hidden IgG Antibodies to the Tumor-Associated Thomsen-Friedenreich Antigen in Gastric Cancer Patients: Lectin Reactivity, Avidity, and Clinical Relevance. PMID: 28316982 Ref: HMGA2 regulates CD44 expression to promote gastric cancer cell motility and sphere formation. PMID: 28337375 Ref: The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer. PMID: 28424413 Ref: REG3A promotes the proliferation, migration, and invasion of gastric cancer cells. PMID: 28435292 Ref: Downregulation of FKBP14 by RNA interference inhibits the proliferation, adhesion and invasion of gastric cancer cells. PMID: 28454471 Ref: Peroxiredoxin 5 overexpression enhances tumorigenicity and correlates with poor prognosis in gastric cancer. PMID: 28535004 Ref: Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-beta/Smad Pathway. PMID: 28539961 Ref: Up-regulation of long non-coding RNA XLOC_010235 regulates epithelial-to-mesenchymal transition to promote metastasis by associating with Snail1 in gastric cancer. PMID: 28550287 Ref: COX-2 regulates Snail expression in gastric cancer via the Notch1 signaling pathway. PMID: 28586004 Ref: Snail Enhances Glycolysis in the Epithelial-Mesenchymal Transition Process by Targeting FBP1 in Gastric Cancer. PMID: 28848200 Ref: LncRNA TRERNA1 Function as an Enhancer of SNAI1 Promotes Gastric Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition. PMID: 28918030 Ref: Hispolon as an inhibitor of TGF-beta-induced epithelial-mesenchymal transition in human epithelial cancer cells by co-regulation of TGF-beta-Snail/Twist axis. PMID: 29085494 Ref: [IL-6 promotes gastric cancer cell proliferation and EMT through regulating miR-152/PIK3R3 pathway]. PMID: 29187649 Ref: miR-302b inhibits tumorigenesis by targeting EphA2 via Wnt/ beta-catenin/EMT signaling cascade in gastric cancer. PMID: 29273006 |
Ref: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. PMID: 28915664 Ref: Protein arginine methyltransferase 1 coordinates the epithelial-mesenchymal transition/proliferation dichotomy in gastric cancer cells. PMID: 29097184 Ref: FBXO31 Suppresses Gastric Cancer EMT by Targeting Snail1 for Proteasomal Degradation. PMID: 29117943 Ref: miR-200c inhibits TGF-beta-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer. PMID: 29302045 Ref: Regulation of drug resistance and metastasis of gastric cancer cells via the microRNA647-ANK2 axis. PMID: 29328428 Ref: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. PMID: 29328491 Ref: Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy. PMID: 29401583 Ref: Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells. PMID: 29409467 Ref: Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2-MEK1/2-ERK1/2 Signaling. PMID: 29549164 Ref: Downregulation of miR-491-5p promotes gastric cancer metastasis by regulating SNAIL and FGFR4. PMID: 29569792 Ref: [beta-Lapachone combined with NVP-BEZ235 inhibit proliferation and migration of BGC-823 gastric cancer cells]. PMID: 29673455 Ref: Molecular mechanism of Poria cocos combined with oxaliplatin on the inhibition of epithelial-mesenchymal transition in gastric cancer cells. PMID: 29710543 Ref: DNA methyltransferase 3A isoform b contributes to repressing E-cadherin through cooperation of DNA methylation and H3K27/H3K9 methylation in EMT-related metastasis of gastric cancer. PMID: 29717263 Ref: Isolation and identification of chemotherapy-enriched sphere-forming cells from a patient with gastric cancer. PMID: 29744869 Ref: MEG3/miR21 axis affects cell mobility by suppressing epithelialmesenchymal transition in gastric cancer. PMID: 29749532 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Validation of Neurotensin Receptor 1 as a Therapeutic Target for Gastric Cancer. PMID: 29794962 Ref: DSGOST regulates resistance via activation of autophagy in gastric cancer. PMID: 29844404 Ref: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. PMID: 29858600 Ref: Sorting nexin-1 is a candidate tumor suppressor and potential prognostic marker in gastric cancer. PMID: 29868263 Ref: MiR-361-5p inhibits the mobility of gastric cancer cells through suppressing epithelial-mesenchymal transition via the Wnt/beta-catenin pathway. PMID: 29960070 Ref: Overexpression of FGFR1 Promotes Peritoneal Dissemination Via Epithelial-to-Mesenchymal Transition in Gastric Cancer. PMID: 29976636 Ref: Upregulation of EphB3 in gastric cancer with acquired resistance to a FGFR inhibitor. PMID: 30044964 Ref: Melatonin inhibits epithelialtomesenchymal transition in gastric cancer cells via attenuation of IL1beta/NFkappaB/MMP2/MMP9 signaling. PMID: 30066836 Ref: CircRBMS3 promotes gastric cancer tumorigenesis by regulating miR-153-SNAI1 axis. PMID: 30132886 Ref: Long non-coding RNA-ENST00000434223 suppresses tumor progression in gastric cancer cells through the Wnt/beta-catenin signaling pathway. PMID: 30138664 Ref: Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer. PMID: 30202514 Ref: SOX4 contributes to TGF-beta-induced epithelial-mesenchymal transition and stem cell characteristics of gastric cancer cells. PMID: 30258935 Ref: HOXB9 inhibits proliferation in gastric carcinoma cells via suppression of phosphorylated-Akt and NF-kappaB-dependent Snail expression. PMID: 30314948 |