Primary Site >> Colorectal Cancer
Gene >> SMARCA4
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Ref: The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. PMID: 11532957 |
Ref: Histone acetylation regulates the cell type specific CIITA promoters, MHC class II expression and antigen presentation in tumor cells. PMID: 16210330 |
Ref: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis. PMID: 21103407 |
Ref: Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells. PMID: 21102582 Ref: Identification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor gene. PMID: 22139574 |
Ref: Mixed adenoneuroendocrine carcinoma of the colon: molecular pathogenesis and treatment. PMID: 25275049 |
Ref: Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer. PMID: 25058500 Ref: Targeting BRG1 chromatin remodeler via its bromodomain for enhanced tumor cell radiosensitivity in vitro and in vivo. PMID: 25504753 Ref: ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression. PMID: 26387539 |
Ref: Bioinformatic exploration of MTA1-regulated gene networks in colon cancer. PMID: 27052252 Ref: BRG1 targeting STAT3/VEGFC signaling regulates lymphangiogenesis in colorectal cancer. PMID: 27145366 Ref: The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A. PMID: 27852072 |
Ref: Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway. PMID: 28182012 Ref: Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. PMID: 28524162 Ref: BRG1 promotes VEGF-A expression and angiogenesis in human colorectal cancer cells. PMID: 28899659 |
Ref: BRG1 is correlated with poor prognosis in colorectal cancer. PMID: 29288038 Ref: Identification of Driver Mutations in Rare Cancers: The Role of SMARCA4 in Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT). PMID: 29423809 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation. PMID: 30076409 |