Primary Site >> Liver Cancer

Gene >> SMAD6

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Ref: Mutational analysis of the Smad6 and Smad7 genes in hepatocellular carcinoma.
PMID: 11408948
Ref: Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta.
PMID: 20196115
Ref: [Effects of Smad4 on liver fibrosis and hepatocarcinogenesis in mice treated with CCl4/ethanol].
PMID: 20196951
Ref: BMP4 administration induces differentiation of CD133+ hepatic cancer stem cells, blocking their contributions to hepatocellular carcinoma.
PMID: 22773665
Ref: Analysis of Notch and TGF-beta Signaling Expression in Different Stages of Disease Progression During Hepatitis B Virus Infection.
PMID: 23238065
Ref: Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach.
PMID: 26300991
Ref: Genomic characterization of liver metastases from colorectal cancer patients.
PMID: 27662660
Ref: Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expression.
PMID: 29352111