Primary Site >> Colorectal Cancer
Gene >> SMAD5
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Ref: Smad5, a tumor suppressor candidate at 5q31.1, is hemizygously lost and not mutated in the retained allele in human leukemia cell line HL60. PMID: 9264367 |
Ref: Expression of Smad proteins in human colorectal cancer. PMID: 10389752 Ref: Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome. PMID: 10446110 Ref: A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization. PMID: 10601642 |
Ref: Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer. PMID: 12209988 |
Ref: Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line. PMID: 25165122 Ref: Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells. PMID: 25218966 |
Ref: Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis. PMID: 26135667 |
Ref: Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1. PMID: 27177089 Ref: Genomic characterization of liver metastases from colorectal cancer patients. PMID: 27662660 |
Ref: Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes. PMID: 28572005 |