Primary Site >> Colorectal Cancer
Gene >> SLIT2
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Ref: Quantification of expression of netrins, slits and their receptors in human prostate tumors. PMID: 12471613 Ref: SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells. PMID: 12615722 Ref: Frequent epigenetic inactivation of the SLIT2 gene in gliomas. PMID: 12881718 |
Ref: Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers. PMID: 15534609 |
Ref: Robo1/Robo4: differential expression of angiogenic markers in colorectal cancer. PMID: 16685377 |
Ref: Epigenetic inactivation of SLIT2 in human hepatocellular carcinomas. PMID: 19100240 Ref: Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia. PMID: 19550140 |
Ref: Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis. PMID: 21283129 Ref: SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated. PMID: 21627385 |
Ref: Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer. PMID: 23010642 |
Ref: Novel methylation panel for the early detection of neoplasia in high-risk ulcerative colitis and Crohn's colitis patients. PMID: 22532293 Ref: Slit/Robo-mediated chemorepulsion of vagal sensory axons in the fetal gut. PMID: 23161783 Ref: SLIT2 inhibits cell migration in colorectal cancer through the AKT-GSK3beta signaling pathway. PMID: 23314850 Ref: DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer. PMID: 23694962 Ref: Decreased expression of miR-218 is associated with poor prognosis in patients with colorectal cancer. PMID: 24294377 |
Ref: Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating Slit2-mediated repulsion. PMID: 23302812 Ref: Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion. PMID: 25056828 |
Ref: USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration. PMID: 25242263 Ref: Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/beta-catenin pathway. PMID: 25605242 Ref: Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas. PMID: 26291085 |
Ref: MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer. PMID: 27462788 Ref: srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer. PMID: 27923383 |
Ref: Candidate predisposing germline copy number variants in early onset colorectal cancer patients. PMID: 27888432 |
Ref: New Methylation Biomarker Panel for Early Diagnosis of Dysplasia or Cancer in High-Risk Inflammatory Bowel Disease Patients. PMID: 30099509 |