Primary Site >> Colorectal Cancer

Gene >> SLCO1B1

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Ref: Molecular genetics of unconjugated hyperbilirubinemia in Taiwanese.
PMID: 15965581
Ref: Single nucleotide polymorphisms of ABCC5 and ABCG1 transporter genes correlate to irinotecan-associated gastrointestinal toxicity in colorectal cancer patients: a DMET microarray profiling study.
PMID: 21892003
Ref: Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.
PMID: 22045187
Ref: Influence of the functional polymorphisms in the organic anion transporting polypeptide 1B1 in the susceptibility to colorectal cancer.
PMID: 23216274
Ref: Tumor-specific expression of organic anion-transporting polypeptides: transporters as novel targets for cancer therapy.
PMID: 23431456
Ref: Regorafenib is transported by the organic anion transporter 1B1 and the multidrug resistance protein 2.
PMID: 25739790
Ref: A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.
PMID: 25963333
Ref: Lack of Interactions Between an Antisense Oligonucleotide with 2'-O-(2-Methoxyethyl) Modifications and Major Drug Transporters.
PMID: 26959999
Ref: Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1.
PMID: 28423714
Ref: Common variants in glucuronidation enzymes and membrane transporters as potential risk factors for colorectal cancer: a case control study.
PMID: 29282011