Primary Site >> Colorectal Cancer

Gene >> SLC22A1

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Ref: Organic cation transporters are determinants of oxaliplatin cytotoxicity.
PMID: 16951202
Ref: Factors affecting sensitivity to antitumor platinum derivatives of human colorectal tumor cell lines.
PMID: 18030470
Ref: cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.
PMID: 18579768
Ref: Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.
PMID: 21051540
Ref: Genetic polymorphisms potentially associated with response to metformin in postmenopausal diabetics suffering and not suffering with cancer.
PMID: 24145224
Ref: Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells.
PMID: 26196503
Ref: Assessment of the Relation between the Expression of Oxaliplatin Transporters in Colorectal Cancer and Response to FOLFOX-4 Adjuvant Chemotherapy: A Case Control Study.
PMID: 26859833
Ref: Lack of Interactions Between an Antisense Oligonucleotide with 2'-O-(2-Methoxyethyl) Modifications and Major Drug Transporters.
PMID: 26959999
Ref: Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
PMID: 28817838
Ref: Relevance of copper transporter 1 and organic cation transporters 1-3 for oxaliplatin uptake and drug resistance in colorectal cancer cells.
PMID: 29417972