Primary Site >> Colorectal Cancer

Gene >> SLC16A3

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Ref: Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms.
PMID: 17760565
 Ref: Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer.
PMID: 22969839
 Ref: Investigation of possible endogenous hypoxia markers in colorectal cancer.
PMID: 22852555
Ref: Expression of monocarboxylate transporter (MCT)-4 in colorectal cancer and its role: MCT4 contributes to the growth of colorectal cancer with vascular endothelial growth factor.
PMID: 23780984
Ref: Downregulation of CD147 expression by RNA interference inhibits HT29 cell proliferation, invasion and tumorigenicity in vitro and in vivo.
PMID: 24064772
 Ref: Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux.
PMID: 24672058
 Ref: Polymorphisms of monocarboxylate transporter genes are associated with clinical outcomes in patients with colorectal cancer.
PMID: 25492048
Ref: Oncostatic effects of fluoxetine in experimental colon cancer models.
PMID: 26004136
 Ref: Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis.
PMID: 27460659
Ref: Lactate-An Integrative Mirror of Cancer Metabolism.
PMID: 27557533
Ref: Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications.
PMID: 28874966
 Ref: MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis.
PMID: 28471448
Ref: Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis.
PMID: 29357130
 Ref: Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells.
PMID: 28846107
Ref: MCT4 Expression Is a Potential Therapeutic Target in Colorectal Cancer with Peritoneal Carcinomatosis.
PMID: 29483215
Ref: The prognostic significance of the expression of monocarboxylate transporter 4 in patients with right- or left-sided colorectal cancer.
PMID: 30270512