Primary Site >> Colorectal Cancer
Gene >> SLC16A1
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Ref: Short-chain fatty acid (SCFA) uptake into Caco-2 cells by a pH-dependent and carrier mediated transport mechanism. PMID: 10918994 Ref: [Microwave coagulation therapy for liver recurrence after resection of metastatic colorectal cancer--comparison with re-hepatectomy]. PMID: 11086427 |
Ref: Transport and uptake of nateglinide in Caco-2 cells and its inhibitory effect on human monocarboxylate transporter MCT1. PMID: 12237260 |
Ref: Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells. PMID: 15452831 Ref: The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasis. PMID: 16042588 |
Ref: Microarray analysis of butyrate regulated genes in colonic epithelial cells. PMID: 16405400 Ref: Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. PMID: 16423989 |
Ref: Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate. PMID: 17663521 |
Ref: Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms. PMID: 17760565 Ref: Blocking CD147 induces cell death in cancer cells through impairment of glycolytic energy metabolism. PMID: 18616931 |
Ref: In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds. PMID: 21207318 |
Ref: Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells. PMID: 22552910 |
Ref: Investigation of possible endogenous hypoxia markers in colorectal cancer. PMID: 22852555 Ref: Laparoscopic resection of primary midgut carcinoid tumors. PMID: 23572224 Ref: Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. PMID: 23994611 Ref: Downregulation of CD147 expression by RNA interference inhibits HT29 cell proliferation, invasion and tumorigenicity in vitro and in vivo. PMID: 24064772 Ref: Butyrate and colorectal cancer: the role of butyrate transport. PMID: 24160296 |
Ref: The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats. PMID: 24454707 Ref: Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux. PMID: 24672058 Ref: Dichloroacetate induces autophagy in colorectal cancer cells and tumours. PMID: 24892448 Ref: EMMPRIN reduction via scFv-M6-1B9 intrabody affects alpha3beta1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2. PMID: 24924201 |
Ref: Polymorphisms of monocarboxylate transporter genes are associated with clinical outcomes in patients with colorectal cancer. PMID: 25492048 Ref: Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells. PMID: 26021766 |
Ref: Influence of high glucose state on bromopyruvate-induced cytotoxity by human colon cancer cell lines. PMID: 26825851 Ref: The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis? PMID: 27346602 Ref: Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. PMID: 27460659 Ref: Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer. PMID: 27729975 Ref: Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. PMID: 28874966 |
Ref: Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells. PMID: 28230866 Ref: MACC1 mediates chemotherapy sensitivity of 5-FU and cisplatin via regulating MCT1 expression in gastric cancer. PMID: 28235486 Ref: A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells. PMID: 28450161 Ref: Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis. PMID: 29357130 |
Ref: Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells. PMID: 28846107 Ref: The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications. PMID: 29848266 |