Primary Site >> Colorectal Cancer

Gene >> SLC10A2

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Ref: An association between genetic polymorphisms in the ileal sodium-dependent bile acid transporter gene and the risk of colorectal adenomas.
PMID: 11535543
Ref: Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps.
PMID: 16844096
Ref: Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes.
PMID: 17960397
Ref: Effects of common haplotypes of the ileal sodium dependent bile acid transporter gene on the development of sporadic and familial colorectal cancer: a case control study.
PMID: 18644122
Ref: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes.
PMID: 18772362
Ref: Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter.
PMID: 19673539
Ref: Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development.
PMID: 25085247
Ref: Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.
PMID: 26210740
Ref: Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport.
PMID: 27929465
Ref: Western Diet Deregulates Bile Acid Homeostasis, Cell Proliferation, and Tumorigenesis in Colon.
PMID: 28416481
Ref: Colorectal cancer specific conditions promote Streptococcus gallolyticus gut colonization.
PMID: 29279402