Primary Site >> Pancreatic Cancer
Gene >> SKP2
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Ref: Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT. PMID: 15572689 |
Ref: High-level Skp2 expression in pancreatic ductal adenocarcinoma: correlation with the extent of lymph node metastasis, higher histological grade, and poorer patient outcome. PMID: 16670630 Ref: IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression. PMID: 16902410 Ref: Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma. PMID: 16951171 |
Ref: SKP2 confers resistance of pancreatic cancer cells towards TRAIL-induced apoptosis. PMID: 21109943 |
Ref: Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A. PMID: 18791364 Ref: Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence. PMID: 24902898 Ref: The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. PMID: 25082960 Ref: Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A. PMID: 25233928 |
Ref: Arsenic Trioxide Inhibits Cell Growth and Invasion via Down- Regulation of Skp2 in Pancreatic Cancer Cells. PMID: 25987041 |
Ref: Nuclear expression of Y-box binding protein-1 is associated with poor prognosis in patients with pancreatic cancer and its knockdown inhibits tumor growth and metastasis in mice tumor models. PMID: 26939718 Ref: Curcumin inhibits cell growth and invasion and induces apoptosis through down-regulation of Skp2 in pancreatic cancer cells. PMID: 27725901 Ref: Rottlerin exhibits anti-cancer effect through inactivation of S phase kinase-associated protein 2 in pancreatic cancer cells. PMID: 27822410 |
Ref: Role of Notch signaling pathway in pancreatic cancer. PMID: 28337369 Ref: Stathmin 1 promotes the proliferation and malignant transformation of pancreatic intraductal papillary mucinous neoplasms. PMID: 28454324 |
Ref: Tetrandrine inhibits deregulated cell cycle in pancreatic cancer cells: Differential regulation of p21(Cip1/Waf1), p27(Kip1) and cyclin D1. PMID: 29605511 Ref: Preprogramming therapeutic response of PI3K/mTOR dual inhibitor via the regulation of EHMT2 and p27 in pancreatic cancer. PMID: 30323973 |