Primary Site >> Colorectal Cancer
Gene >> SKP1
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|
|
Ref: An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin. PMID: 10228155 |
Ref: A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. PMID: 14516475 Ref: Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery. PMID: 14563921 |
Ref: CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. PMID: 16778892 |
Ref: The FBXW7 beta-form is suppressed in human glioma cells. PMID: 17274947 |
Ref: The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity. PMID: 19297328 |
Ref: STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells. PMID: 20407011 |
Ref: FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation. PMID: 21282377 Ref: SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. PMID: 21368833 |
Ref: The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer. PMID: 26114183 |
Ref: Radiosensitization of Human Colorectal Cancer Cells by MLN4924: An Inhibitor of NEDD8-Activating Enzyme. PMID: 26082455 |
Ref: FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma. PMID: 27916606 Ref: CacyBP/SIP promotes the proliferation of colon cancer cells. PMID: 28196083 |