Primary Site >> Biliary tract Cancer

Gene >> SKP1

  • 2007
  • 2017
  • 2018
Ref: FBXW7/hCDC4 is a general tumor suppressor in human cancer.
PMID: 17909001
 Ref: E3 ubiquitin ligase FBW7alpha inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.
PMID: 28184929
 Ref: Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.
PMID: 29386660