Primary Site >> Colorectal Cancer
Gene >> SIRT7
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Ref: Overexpression of sirt7 exhibits oncogenic property and serves as a prognostic factor in colorectal cancer. PMID: 24771643 |
Ref: Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer. PMID: 28435470 Ref: Dicer regulates non-homologous end joining and is associated with chemosensitivity in colon cancer patients. PMID: 28911000 |
Ref: Sirtuin 7 promotes colorectal carcinoma proliferation and invasion through the inhibition of E-cadherin. PMID: 29467843 Ref: Sirtuin 7-mediated deacetylation of WD repeat domain 77 (WDR77) suppresses cancer cell growth by reducing WDR77/PRMT5 transmethylase complex activity. PMID: 30282801 |