Primary Site >> Colorectal Cancer

Gene >> SIAH2

  • 1999
  • 2007
  • 2015
  • 2017
Ref: Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins.
PMID: 9858595
Ref: Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells.
PMID: 17463182
Ref: Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO.
PMID: 25561546
Ref: Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1alpha stabilization.
PMID: 28214471