Primary Site >> Esophagus Cancer
Gene >> SHH
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Ref: Hedgehog signaling is activated in subsets of esophageal cancers. PMID: 16003737 Ref: Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model. PMID: 16488438 Ref: Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response. PMID: 17085672 Ref: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review). PMID: 17089004 Ref: Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma. PMID: 17179732 |
Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 |
Ref: Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer. PMID: 20839260 |
Ref: Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus. PMID: 22509480 |
Ref: Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract. PMID: 25884700 Ref: CD44, SHH and SOX2 as novel biomarkers in esophageal cancer patients treated with neoadjuvant chemoradiotherapy. PMID: 26364884 |
Ref: Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma. PMID: 29416661 |