Primary Site >> Colorectal Cancer

Gene >> SGPL1

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Ref: The human c-Src proto-oncogene promoter contains multiple targets for triplex-forming oligonucleotides.
PMID: 9826266
Ref: Chronic but not acute treatment with conjugated linoleic acid (CLA) isomers (trans-10, cis-12 CLA and cis-9, trans-11 CLA) affects lipid metabolism in Caco-2 cells.
PMID: 12163657
Ref: Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer.
PMID: 17090686
Ref: Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again.
PMID: 17361098
Ref: Mutated ras induced PLD1 gene expression through increased Sp1 transcription factor.
PMID: 19994725
Ref: Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.
PMID: 20068171
Ref: From mininvasive to maxinvasive surgery in colorectal cancer: modem evolution of oncologic specialized units.
PMID: 21066988
Ref: Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.
PMID: 25347472
Ref: Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer.
PMID: 29223361