Primary Site >> Colorectal Cancer

Gene >> SGO1

  • 2009
  • 2011
  • 2012
  • 2013
  • 2016
Ref: Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer.
PMID: 18635744
 Ref: A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion.
PMID: 21532624
 Ref: Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis.
PMID: 22262168
 Ref: Frameshift mutations of chromosome cohesion-related genes SGOL1 and PDS5B in gastric and colorectal cancers with high microsatellite instability.
PMID: 23850494
 Ref: Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice.
PMID: 26833665