Primary Site >> Colorectal Cancer
Gene >> SFRP2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Methylation changes in faecal DNA: a marker for colorectal cancer screening? PMID: 15094274 |
Ref: Comparative genomics on SFRP1 orthologs. PMID: 16077939 Ref: Comparative genomics on SFRP2 orthologs. PMID: 16077992 Ref: Mutant KRAS in aberrant crypt foci (ACF): initiation of colorectal cancer? PMID: 16219426 |
Ref: WNT antagonist, SFRP1, is Hedgehog signaling target. PMID: 16328026 Ref: Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor. PMID: 17131472 |
Ref: Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. PMID: 17297461 Ref: Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions. PMID: 17352030 Ref: Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps. PMID: 17378912 Ref: Hypermethylation of SFRP2 as a potential marker for stool-based detection of colorectal cancer and precancerous lesions. PMID: 17410438 Ref: Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. PMID: 18056424 Ref: [Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. PMID: 18396643 |
Ref: SFRP2 methylation in fecal DNA--a marker for colorectal polyps. PMID: 17639423 Ref: Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening. PMID: 18203283 Ref: Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa. PMID: 18542073 Ref: Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia. PMID: 18716850 Ref: Silencing of secreted frizzled-related protein genes in MSI colorectal carcinogenesis. PMID: 18795670 |
Ref: FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis. PMID: 19557575 Ref: Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. PMID: 19700653 Ref: Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. PMID: 19934284 |
Ref: Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa. PMID: 20395289 Ref: Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer. PMID: 20403915 Ref: Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer. PMID: 20682398 Ref: Epigenetic inactivation of tumor suppressor SFRP2 and point mutation in KRAS proto-oncogene in fistula-associated mucinous type anal adenocarcinoma: report of two cases. PMID: 20686305 Ref: Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patients. PMID: 21033217 |
Ref: Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression. PMID: 21068132 Ref: Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: a phase I pilot study. PMID: 21123457 Ref: Diagnostic and prognostic value of the methylation status of secreted frizzled-related protein 2 in colorectal cancer. PMID: 21463549 Ref: DNA methylation predicts recurrence from resected stage III proximal colon cancer. PMID: 21509761 Ref: Genistein attenuates WNT signaling by up-regulating sFRP2 in a human colon cancer cell line. PMID: 21571909 |
Ref: Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. PMID: 22132744 Ref: Identifying microRNA-mRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysis. PMID: 22703586 |
Ref: Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/beta-catenin signalling and reduces colon pre-neoplasia in rats. PMID: 22716201 Ref: Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening. PMID: 23320751 Ref: Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cells. PMID: 23368921 Ref: DNA methylation and histone modifications of Wnt genes by genistein during colon cancer development. PMID: 23598468 Ref: Effects of iodine-125 seeds on the methylation of SFRP2 and P16 in colorectal cancer. PMID: 24223648 Ref: Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas. PMID: 24350795 |
Ref: Differential survival trends of stage II colorectal cancer patients relate to promoter methylation status of PCDH10, SPARC, and UCHL1. PMID: 24309322 Ref: Validation of methylation-sensitive high-resolution melting (MS-HRM) for the detection of stool DNA methylation in colorectal neoplasms. PMID: 24518356 Ref: The specific methylation characteristics of cancer related genes in Chinese colorectal cancer patients. PMID: 24852431 Ref: Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer. PMID: 24876755 Ref: Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. PMID: 25053594 Ref: Promoter methylation analysis of WNT/beta-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer. PMID: 25107489 Ref: Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer. PMID: 25139296 Ref: DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNA. PMID: 25202404 Ref: Accuracy of early detection of colorectal tumours by stool methylation markers: a meta-analysis. PMID: 25320544 Ref: Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists. PMID: 25432628 |
Ref: Comparison of Automated and Manual DNA Isolation Methods for DNA Methylation Analysis of Biopsy, Fresh Frozen, and Formalin-Fixed, Paraffin-Embedded Colorectal Cancer Samples. PMID: 25576093 Ref: Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas. PMID: 25759530 Ref: MGMT-B gene promoter hypermethylation in patients with inflammatory bowel disease - a novel finding. PMID: 25773792 Ref: Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/beta-catenin pathways: genome-wide analysis using MeDIP-seq. PMID: 26101583 Ref: Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas. PMID: 26291085 Ref: DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer. PMID: 26482433 Ref: [Fecal Biomarker for Colorectal Cancer Diagnosis]. PMID: 26524859 |
Ref: Early detection of colorectal cancer: from conventional methods to novel biomarkers. PMID: 25687380 Ref: The variation trends of SFRP2 methylation of tissue, feces, and blood detection in colorectal cancer development. PMID: 26258809 Ref: Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma. PMID: 26756304 Ref: MicroRNA-224 sustains Wnt/beta-catenin signaling and promotes aggressive phenotype of colorectal cancer. PMID: 26822534 Ref: Hypermethylated DNA as a biomarker for colorectal cancer: a systematic review. PMID: 26998585 Ref: Field Cancerization in Sporadic Colon Cancer. PMID: 27114416 Ref: Sensitive and Noninvasive Detection of Aberrant SFRP2 and MGMT-B Methylation in Iranian Patients with Colon Polyps. PMID: 27221916 Ref: Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer. PMID: 27245242 Ref: miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression. PMID: 27494869 Ref: KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients. PMID: 27540971 Ref: DNA methylation analysis of secreted frizzled-related protein 2 gene for the early detection of colorectal cancer in fecal DNA. PMID: 27630389 Ref: Methylation of SFRP2 gene as a promising noninvasive biomarker using feces in colorectal cancer diagnosis: a systematic meta-analysis. PMID: 27659069 Ref: MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition. PMID: 27668319 Ref: Diagnostic value of secreted frizzled-related protein 2 gene promoter hypermethylation in stool for colorectal cancer: A meta-analysis. PMID: 27721248 |
Ref: Induction of Epigenetic Alteration by CPUK02, An Ent- kaurenoid Derivative of Stevioside. PMID: 28090275 Ref: Identification of Methylation Profiles of Cancer-related Genes in Circulating Tumor Cells Population. PMID: 28314271 Ref: Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats. PMID: 28451581 Ref: Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa. PMID: 28533824 Ref: Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples. PMID: 28753106 Ref: Comparison of a prototype reverse hybridization assay and MethyLight for detection of SFRP2 promotor methylation in fecal DNA. PMID: 28777432 Ref: Screening of exon methylation biomarkers for colorectal cancer via LC-MS/MS strategy. PMID: 28940471 Ref: Is methylation analysis of SFRP2, TFPI2, NDRG4, and BMP3 promoters suitable for colorectal cancer screening in the Korean population? PMID: 29142517 |
Ref: Chemoprevention of colorectal cancer by black raspberry anthocyanins involved the modulation of gut microbiota and SFRP2 demethylation. PMID: 29361151 Ref: Blood Collection and Cell-Free DNA Isolation Methods Influence the Sensitivity of Liquid Biopsy Analysis for Colorectal Cancer Detection. PMID: 29374860 Ref: HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer. PMID: 29504907 Ref: The importance of stool DNA methylation in colorectal cancer diagnosis: A meta-analysis. PMID: 30024936 Ref: Circulating Free Methylated Tumor DNA Markers for Sensitive Assessment of Tumor Burden and Early Response Monitoring in Patients Receiving Systemic Chemotherapy for Colorectal Cancer Liver Metastasis. PMID: 30080722 Ref: Hypermethylated Promoters of Secreted Frizzled-Related Protein Genes are Associated with Colorectal Cancer. PMID: 30368728 |