Primary Site >> Stomach Cancer
Gene >> SFRP1
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Ref: A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. PMID: 11992124 |
Ref: Epithelial-mesenchymal transition in gastric cancer (Review). PMID: 16273224 |
Ref: WNT antagonist, SFRP1, is Hedgehog signaling target. PMID: 16328026 Ref: Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. PMID: 17035233 Ref: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review). PMID: 17089004 |
Ref: Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. PMID: 17297461 Ref: Hypermethylation and aberrant expression of Wnt antagonist secreted frizzled-related protein 1 in gastric cancer. PMID: 17465504 Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. PMID: 17568183 Ref: Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. PMID: 17848950 Ref: Oligonucleotide array comparative genomic hybridization refines the structure of 8p23.1, 17q12 and 20q13.2 amplifications in gastric carcinomas. PMID: 18160780 |
Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 |
Ref: Contrasting activity of Hedgehog and Wnt pathways according to gastric cancer cell differentiation: relevance of crosstalk mechanisms. PMID: 19930158 Ref: Molecular analysis of gastric differentiated-type intramucosal and submucosal cancers. PMID: 20178104 |
Ref: Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. PMID: 21567192 Ref: Decreased expression and aberrant hypermethylation of the SFRP genes in human gastric cancer. PMID: 21830441 |
Ref: Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling. PMID: 22246241 |
Ref: High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer. PMID: 23927957 Ref: Examination of whole blood DNA methylation as a potential risk marker for gastric cancer. PMID: 23943784 |
Ref: Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk. PMID: 23942619 Ref: MicroRNA-206 suppresses gastric cancer cell growth and metastasis. PMID: 24855559 |
Ref: Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer. PMID: 24510342 Ref: Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes. PMID: 25479246 |
Ref: Low expression of RBMS3 and SFRP1 are associated with poor prognosis in patients with gastric cancer. PMID: 27904780 |
Ref: Genetic variants in the 3' untranslated region of sFRP1 gene and risk of gastric cancer in a Chinese population. PMID: 27739564 Ref: Epigenetic regulation of Wnt/beta-catenin signal-associated genes in gastric neoplasia of the fundic gland (chief cell-predominant) type. PMID: 28105693 Ref: Secreted frizzled-related protein 1 overexpression in gastric cancer: Relationship with radiological findings of dual-energy spectral CT and PET-CT. PMID: 28169332 Ref: MiRNA-27a promotes the proliferation and invasion of human gastric cancer MGC803 cells by targeting SFRP1 via Wnt/beta-catenin signaling pathway. PMID: 28401000 |
Ref: Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT. PMID: 29443079 Ref: MiR-208a enhances cell proliferation and invasion of gastric cancer by targeting SFRP1 and negatively regulating MEG3. PMID: 29886152 |