Primary Site >> Colorectal Cancer
Gene >> SENP1
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Ref: SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors. PMID: 21669491 Ref: Reversible SUMOylation of TBL1-TBLR1 regulates beta-catenin-mediated Wnt signaling. PMID: 21777810 |
Ref: Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype. PMID: 24658599 Ref: The bacterial genotoxin colibactin promotes colon tumor growth by modifying the tumor microenvironment. PMID: 25483338 |
Ref: Identification of SENP1 inhibitors through in silico screening and rational drug design. PMID: 27344494 |
Ref: miR-133a-3p Targets SUMO-Specific Protease 1 to Inhibit Cell Proliferation and Cell Cycle Progress in Colorectal Cancer. PMID: 28748780 |