Primary Site >> Colorectal Cancer

Gene >> SELENOP

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Ref: A complex DNA-repeat structure within the Selenoprotein P promoter contains a functionally relevant polymorphism and is genetically unstable under conditions of mismatch repair deficiency.
PMID: 12173025
 Ref: Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and present carriers of colon adenomas.
PMID: 14690787
 Ref: Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis.
PMID: 15203372
 Ref: Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer.
PMID: 17912428
 Ref: Aberrant expression of selenoproteins in the progression of colorectal cancer.
PMID: 18054426
Ref: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.
PMID: 18483336
 Ref: Relative abundance of selenoprotein P isoforms in human plasma depends on genotype, se intake, and cancer status.
PMID: 19453253
 Ref: Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon.
PMID: 20346189
Ref: Genetic variants in selenoprotein genes increase risk of colorectal cancer.
PMID: 20378690
Ref: Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction.
PMID: 20542496
 Ref: Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer.
PMID: 23970932
 Ref: Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort.
PMID: 25042282
Ref: Potential anticancer properties and mechanisms of action of curcumin.
PMID: 25667441
Ref: Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage.
PMID: 26053663
 Ref: Selenoprotein P in colitis-associated carcinoma.
PMID: 27314080
 Ref: Selenoproteins and oxidative stress-induced inflammatory tumorigenesis in the gut.
PMID: 27563706
 Ref: Roles for selenium and selenoprotein P in the development, progression, and prevention of intestinal disease.
PMID: 29778465