Primary Site >> Colorectal Cancer
Gene >> SELE
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Ref: An inducible endothelial cell surface glycoprotein mediates melanoma adhesion. PMID: 2588007 |
Ref: Endothelial leukocyte adhesion molecule 1: direct expression cloning and functional interactions. PMID: 1689848 Ref: A blocking monoclonal antibody to endothelial-leukocyte adhesion molecule-1 (ELAM1). PMID: 1697461 |
Ref: Expression and functional characterization of a soluble form of endothelial-leukocyte adhesion molecule 1. PMID: 1711067 Ref: Tumor cell adhesion to endothelial cells: endothelial leukocyte adhesion molecule-1 as an inducible adhesive receptor specific for colon carcinoma cells. PMID: 1715924 Ref: Role of beta 1 integrins in tumor cell adhesion to cultured human endothelial cells. PMID: 1753702 |
Ref: Effect of benzyl-alpha-GalNAc, an inhibitor of mucin glycosylation, on cancer-associated antigens in human colon cancer cells. PMID: 1284381 Ref: Endothelial leukocyte adhesion molecule-1-dependent adhesion of colon carcinoma cells to vascular endothelium is inhibited by an antibody to Lewis fucosylated type I carbohydrate chain. PMID: 1371572 Ref: Recombinant E-selectin-protein mediates tumor cell adhesion via sialyl-Le(a) and sialyl-Le(x). PMID: 1371681 Ref: Granule membrane protein 140 (GMP140) binds to carcinomas and carcinoma-derived cell lines. PMID: 1372439 |
Ref: Rolling and adhesion of human tumor cells on vascular endothelium under physiological flow conditions. PMID: 7504697 Ref: COLO 205 utilizes E-selectin to adhere to human endothelium. PMID: 7685674 Ref: Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammation. PMID: 7694675 Ref: Colorectal cancer metastasis determined by carbohydrate-mediated cell adhesion: role of sialyl-LeX antigens. PMID: 7903054 Ref: Biosynthesis and regulation of Le(x) and SA-Le(x) glycolipids in metastatic human colon carcinoma cells. PMID: 7911780 |
Ref: Differential E-selectin-dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials. PMID: 7507108 Ref: Inositol polyanions. Noncarbohydrate inhibitors of L- and P-selectin that block inflammation. PMID: 7515048 Ref: Cell adhesion molecule expression within the microvasculature of human colorectal malignancies. PMID: 7517347 Ref: A secreted mucin carrying sialyl-Lewis a from colon carcinoma cells binds to E-selectin and inhibits HL-60 cell adhesion. PMID: 7527376 Ref: The relative roles of vitronectin receptor, E-selectin and alpha 4 beta 1 in cancer cell adhesion to interleukin-1-treated endothelial cells. PMID: 7531992 |
Ref: E-selectin-mediated dynamic interactions of breast- and colon-cancer cells with endothelial-cell monolayers. PMID: 7530236 Ref: Role of SPan-1 antigen in adhesion of human colon cancer cells to vascular endothelium. PMID: 7537192 Ref: Expression of E-selectin on endothelial cells of small veins in human colorectal cancer. PMID: 7538975 Ref: Cell adhesion molecule expression by vascular endothelial cells as an immune/inflammatory reaction in human colon carcinoma. PMID: 7542647 Ref: [E-selectin expression in serum and tissue correlates with distant metastasis of colorectal cancer]. PMID: 7543166 Ref: Differential colon cancer cell adhesion to E-, P-, and L-selectin: role of mucin-type glycoproteins. PMID: 7545541 Ref: [Structures, synthesis and functions of sialyl Le(a)/sialyl Le(x) antigens]. PMID: 7630014 Ref: Increased expression of sialyl Lewis A and sialyl Lewis X in liver metastases of human colorectal carcinoma. PMID: 8621274 |
Ref: [Carbohydrate antigens in carcinoma invasion and metastasis]. PMID: 8632742 Ref: Effect of O-glycosylated mucin on invasion and metastasis of HM7 human colon cancer cells. PMID: 8651907 Ref: An E-selectin-IgG chimera supports sialylated moiety dependent adhesion of colon carcinoma cells under fluid flow. PMID: 8669721 Ref: Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression. PMID: 8674277 Ref: Secreted MUC1 mucins lacking their cytoplasmic part and carrying sialyl-Lewis a and x epitopes from a tumor cell line and sera of colon carcinoma patients can inhibit HL-60 leukocyte adhesion to E-selectin-expressing endothelial cells. PMID: 8707893 Ref: Elevated serum E-selectin in patients with liver metastases of colorectal cancer. PMID: 8758256 Ref: E-selectin: sialyl Lewis, a dependent adhesion of colon cancer cells, is inhibited differently by antibodies against E-selectin ligands. PMID: 8795712 Ref: [Sialosyl-Le(a) and Sialosyl-Le(x) antigens in adhesion of cancer cells and tumor progression]. PMID: 8927583 |
Ref: Novel glycoproteins inhibiting the binding of colorectal cancer cells to E-selectin. PMID: 9076523 Ref: Involvement of carbohydrate antigen sialyl Lewis(x) in colorectal cancer metastasis. PMID: 9106690 Ref: Comparison of sialyl-Lewis a-carrying CD43 and MUC1 mucins secreted from a colon carcinoma cell line for E-selectin binding and inhibition of leukocyte adhesion. PMID: 9143414 Ref: Metabolic changes of E-selectin caused by the binding of a mucin carrying sialylLewis A antigens. PMID: 9175751 Ref: Adhesion of HT-29 colon carcinoma cells to E-selectin results in increased tyrosine phosphorylation and decreased activity of c-src. PMID: 9178821 Ref: Inhibition of colon carcinoma cell lung colony formation by a soluble form of E-selectin. PMID: 9212748 Ref: Serum levels of endothelial and neural cell adhesion molecules in prostate cancer. PMID: 9254901 |
Ref: Over-expression of ICAM-1, VCAM-1 and ELAM-1 might influence tumor progression in colorectal cancer. PMID: 9495363 Ref: Serum cell adhesion molecules in patients with colorectal cancer. PMID: 9548306 Ref: Role of sialosyl Lewis(a) in adhesion of colon cancer cells--the antisense RNA approach. PMID: 9578490 Ref: Liver metastasis and adhesion to the sinusoidal endothelium by human colon cancer cells is related to mucin carbohydrate chain length. PMID: 9590134 Ref: Relationship between serum ELAM-1 and metastasis among patients with colon cancer. PMID: 9645747 Ref: Serum concentrations of soluble adhesion molecules in patients with colorectal cancer. PMID: 9667659 Ref: Comparison of 16 human colon carcinoma cell lines for their expression of sialyl LeX antigens and their E-selectin-dependent adhesion. PMID: 9872604 Ref: Adhesion of colorectal carcinoma cells to the endothelium is mediated by cytokines from CEA stimulated Kupffer cells. PMID: 10211983 |
Ref: Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro. PMID: 10411100 Ref: Are selectins involved in metastasis? PMID: 10432003 Ref: Effect of shear stress and a stable prostaglandin I2 analogue on adhesive interactions of colon cancer cells and endothelial cells. PMID: 10469043 |
Ref: Human colon cancer cells express multiple glycoprotein ligands for E-selectin. PMID: 10639580 Ref: E-selectin can mediate the arrest type of adhesion of colon cancer cells under physiological shear flow. PMID: 10741305 Ref: Interaction of tumor cells with vascular endothelia: role of platelet-activating factor. PMID: 11206844 |
Ref: Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells. PMID: 11448946 Ref: Colon cancer cell adhesion to endothelial E-selectin inhibits detachment of endothelial cells through activation of beta(1)-integrin. PMID: 11485302 Ref: Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients: correlations with clinicopathological features, patient survival and tumour surgery. PMID: 11720833 Ref: Paired tumor marker of soluble E-selectin and its ligand sialyl Lewis A in colorectal cancer. PMID: 11777210 Ref: Sialosyl Le(a)-carrying gangliosides present on the surface of colon carcinoma cells are not directly involved in adhesion to E-selectin. PMID: 11831392 Ref: Tumor cell MUC1 and CD43 are glycosylated differently with sialyl-Lewis a and x epitopes and show variable interactions with E-selectin under physiological flow conditions. PMID: 12820726 |
Ref: Leukocyte recruitment in colon cancer: role of cell adhesion molecules, nitric oxide, and transforming growth factor beta1. PMID: 11910362 Ref: E-selectin modulates the malignant properties of T84 colon carcinoma cells. PMID: 12051773 Ref: Hepatic ischemia-reperfusion promotes liver metastasis of colon cancer. PMID: 12121713 Ref: Effect of pro-inflammatory stimuli on tumor cell-mediated induction of endothelial cell adhesion molecules in vitro. PMID: 12127053 Ref: Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis. PMID: 12359742 Ref: Differential endothelial CAM-expression after stimulation with supernatants of LPS- and cytokine-stimulated HT-29 and ST-ML-12 tumor cells growing as monolayer cultures and multicellular spheroids. PMID: 12529976 |
Ref: Role of calcium in E-selectin induced phenotype of T84 colon carcinoma cells. PMID: 12589798 Ref: Expression levels of FUT6 gene transfected into human colon carcinoma cells switch two sialyl-Lewis X-related carbohydrate antigens with distinct properties in cell adhesion. PMID: 12670495 Ref: Different phenotypes of colon carcinoma cells interacting with endothelial cells: role of E-selectin and ultrastructural data. PMID: 12684869 Ref: Prognostic role of serum sialyl Lewisx (CD15s) in colorectal cancer. PMID: 12837983 |
Ref: Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion. PMID: 14630701 Ref: Ionizing radiation-induced E-selectin gene expression and tumor cell adhesion is inhibited by lovastatin and all-trans retinoic acid. PMID: 14988223 Ref: Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. PMID: 15141079 Ref: Loss of disialyl Lewis(a), the ligand for lymphocyte inhibitory receptor sialic acid-binding immunoglobulin-like lectin-7 (Siglec-7) associated with increased sialyl Lewis(a) expression on human colon cancers. PMID: 15231659 Ref: Serum levels of soluble E-selectin in colorectal cancer. PMID: 15254658 Ref: Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin beta4. PMID: 15387376 Ref: Attachment of human colon cancer cells to vascular endothelium is enhanced by N-acetylglucosaminyltransferase V. PMID: 15452379 |
Ref: Expression of the high-affinity selectin glycan ligand C2-O-sLeX by colon carcinoma cells. PMID: 15596301 Ref: CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. PMID: 15994957 Ref: [An interesting change of E-selectin in cimetidine administration during anticancer drug use]. PMID: 16315875 Ref: Inhibition of cellular adhesion in human umbilical vein endothelial cells by NF-kappaB inhibitor DHMEQ under flow. PMID: 17822279 |
Ref: Antithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells. PMID: 16440418 Ref: HCELL is the major E- and L-selectin ligand expressed on LS174T colon carcinoma cells. PMID: 16565092 Ref: Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases. PMID: 16715142 Ref: Death receptor-3, a new E-Selectin counter-receptor that confers migration and survival advantages to colon carcinoma cells by triggering p38 and ERK MAPK activation. PMID: 16982754 Ref: Study of interleukin-6 in the spread of colorectal cancer: the diagnostic significance of IL-6. PMID: 17189976 |
Ref: Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands. PMID: 17135256 Ref: Role of S128R polymorphism of E-selectin in colon metastasis formation. PMID: 17372905 Ref: The host inflammatory response promotes liver metastasis by increasing tumor cell arrest and extravasation. PMID: 17456781 Ref: A cholesterol-independent membrane microdomain serves as a functional counter-receptor for E-selectin at the Colo201 cell surface and initiates signalling on E-selectin binding. PMID: 17684030 Ref: Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture. PMID: 17876298 |
Ref: E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release. PMID: 18324679 Ref: Mechanisms by which E-selectin regulates diapedesis of colon cancer cells under flow conditions. PMID: 18593916 Ref: Crossing the endothelium: E-selectin regulates tumor cell migration under flow conditions. PMID: 19262108 |
Ref: Different roles of galectin-9 isoforms in modulating E-selectin expression and adhesion function in LoVo colon carcinoma cells. PMID: 18401566 Ref: Does colorectal cancer clinical advancement affect adhesion molecules (sP-selectin, sE-selectin and ICAM-1) concentration? PMID: 19136145 Ref: Higher CO2-insufflation pressure inhibits the expression of adhesion molecules and the invasion potential of colon cancer cells. PMID: 19522021 Ref: [Galectin-9 isoforms influence the adhesion between colon carcinoma LoVo cells and human umbilical vein endothelial cells in vitro by regulating the expression of E-selectin in LoVo cells]. PMID: 19538882 Ref: Impact of surgery on local and systemic responses of cytokines and adhesion molecules. PMID: 19950788 |
Ref: E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung. PMID: 20010946 Ref: IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. PMID: 20228195 Ref: Serum sE-selectin levels and carcinoembryonic antigen mRNA-expressing cells in peripheral blood as prognostic factors in colorectal cancer patients. PMID: 20336782 Ref: Significance of serum concentrations of E-selectin and CA19-9 in the prognosis of colorectal cancer. PMID: 20576794 Ref: DNAzyme as an efficient tool to modulate invasiveness of human carcinoma cells. PMID: 20725651 |
Ref: 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating beta-galactoside:alpha2,3-sialyltransferase 6 gene. PMID: 21168523 Ref: Cimetidine inhibits the adhesion of gastric cancer cells expressing high levels of sialyl Lewis x in human vascular endothelial cells by blocking E-selectin expression. PMID: 21327325 Ref: Lunasin induces apoptosis and modifies the expression of genes associated with extracellular matrix and cell adhesion in human metastatic colon cancer cells. PMID: 21462330 Ref: Isolation of endothelial cells from human tumors. PMID: 21516410 Ref: Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4. PMID: 21521691 Ref: Lectin histochemistry of metastasizing and non-metastasizing breast and colon cancer cells. PMID: 21617214 Ref: Morphine attenuates endothelial cell adhesion molecules induced by the supernatant of LPS-stimulated colon cancer cells. PMID: 21655059 Ref: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3. PMID: 21722370 |
Ref: Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition. PMID: 22547830 Ref: Prognostic value of tumor growth factor levels during chemotherapy in patients with metastatic colorectal cancer. PMID: 22580817 Ref: Pre-diagnostic levels of adiponectin and soluble vascular cell adhesion molecule-1 are associated with colorectal cancer risk. PMID: 22719189 Ref: Inducing apoptosis in rolling cancer cells: a combined therapy with aspirin and immobilized TRAIL and E-selectin. PMID: 22724630 |
Ref: Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. PMID: 23401226 |
Ref: Pharmacogenetic predictors of outcome in patients with stage II and III colon cancer treated with oxaliplatin and fluoropyrimidine-based adjuvant chemotherapy. PMID: 24980946 Ref: Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer. PMID: 25213663 |
Ref: 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-kappaB activation. PMID: 27278328 |
Ref: p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription. PMID: 27926494 Ref: Selectin Ligands Sialyl-Lewis a and Sialyl-Lewis x in Gastrointestinal Cancers. PMID: 28241499 |
Ref: p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells. PMID: 29402939 |