Primary Site >> Colorectal Cancer
Gene >> SAT1
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Ref: Effect of expression of human spermidine/spermine N1-acetyltransferase in Escherichia coli. PMID: 7873553 |
Ref: Inhibition of cell growth in CaCO2 cells by the polyamine analogue N1,N12-bis(ethyl)spermine is preceded by a reduction in MYC oncoprotein levels. PMID: 9462700 |
Ref: Surgical treatment of cancer of the colon or rectum. Patient Care Committee of the Society for Surgery of the Alimentary Tract (SSAT). PMID: 10885947 |
Ref: Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells. PMID: 11737227 |
Ref: DNA microarray technology reveals similar gene expression patterns in rats with vitamin a deficiency and chemically induced colitis. PMID: 12163651 |
Ref: Polyamines as modifiers of genetic risk factors in human intestinal cancers. PMID: 12653645 Ref: Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling. PMID: 12907638 Ref: Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer. PMID: 14506281 |
Ref: Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells. PMID: 14750214 |
Ref: Effects of N1, N13-diethylnorspermine (DENSPM) and X-radiation treatment on human colorectal tumor clones with varying X-radiation and drug responses. PMID: 15799689 |
Ref: Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells. PMID: 16262603 Ref: Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer. PMID: 16510598 Ref: Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. PMID: 16637064 Ref: Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism. PMID: 16849586 Ref: Peroxisome proliferator-activated receptor gamma and spermidine/spermine N1-acetyltransferase gene expressions are significantly correlated in human colorectal cancer. PMID: 16854216 |
Ref: Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR. PMID: 17119850 Ref: The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells. PMID: 17237273 Ref: Profiling of selenomethionine responsive genes in colon cancer by microarray analysis. PMID: 17374985 Ref: SSAT patient care guidelines. Surgical treatment of cancer of the colon or rectum. PMID: 18062070 |
Ref: Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine. PMID: 17987291 Ref: Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro. PMID: 18430370 Ref: Identification and characterization of a diamine exporter in colon epithelial cells. PMID: 18660501 Ref: Adenovirus-mediated expression of spermidine/spermine N1-acetyltransferase gene induces S-phase arrest in human colorectal cancer cells. PMID: 18949426 |
Ref: Spermidine/spermine N1-acetyltranferase modulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistant human ovarian cancer cell lines. PMID: 20031193 |
Ref: COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines. PMID: 22159752 Ref: Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells. PMID: 22294330 |
Ref: Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells. PMID: 26704566 |
Ref: Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/beta-catenin signaling pathways in hepatocellular and colorectal carcinoma cells. PMID: 27901475 Ref: Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy. PMID: 28017891 Ref: Impact of Abdominal Adipose Depots and Race on Risk for Colorectal Cancer: A Case-Control Study. PMID: 28323443 Ref: Apigenin Inhibits Human SW620 Cell Growth by Targeting Polyamine Catabolism. PMID: 28572828 |
Ref: Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner. PMID: 29492901 Ref: Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. PMID: 30138353 Ref: SSAT State-of-the-Art Conference: Advances in the Management of Rectal Cancer. PMID: 30215203 Ref: Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets. PMID: 30257361 |