Primary Site >> Colorectal Cancer

Gene >> SART3

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Ref: Production of monoclonal antibodies specific to the carboxyl terminal region of the 85 kDa subunit of phosphatidylinositol 3-kinase: use of the antibodies in recognition of mutant p85.
PMID: 7541019
Ref: A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a Gq/11 protein, phosphatidylinositol 3-kinase beta, and protein kinase Cepsilon.
PMID: 9822674
Ref: Down regulation of the expression of the p110, p85 and p55 subunits of phosphatidylinositol 3-kinase during colon cancer cell anchorage-independent growth.
PMID: 10628371
Ref: Induction of cellular immune responses to tumor cells and peptides in colorectal cancer patients by vaccination with SART3 peptides.
PMID: 11751487
Ref: Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor.
PMID: 11756194
Ref: Expression of tumor rejection antigens in colorectal carcinomas.
PMID: 11920522
Ref: Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells.
PMID: 16609991
Ref: BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers.
PMID: 17384678
Ref: Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line.
PMID: 17923279
Ref: Retinol decreases phosphatidylinositol 3-kinase activity in colon cancer cells.
PMID: 17918208
Ref: Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation.
PMID: 19962665
Ref: The p110alpha and p110beta isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells.
PMID: 20953381
Ref: p37delta is a new isoform of PI3K p110delta that increases cell proliferation and is overexpressed in tumors.
PMID: 22020336
Ref: [Polypeptide P110 enhances the growth-inhibitory effect of cisplatin on colon cancer HCT-116 cells and xenotransplanted tumors in mice].
PMID: 23291128
Ref: Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.
PMID: 26863299
Ref: Dehydroglyasperin D Inhibits the Proliferation of HT-29 Human Colorectal Cancer Cells Through Direct Interaction With Phosphatidylinositol 3-kinase.
PMID: 27051646
Ref: Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
PMID: 28819788