Primary Site >> Biliary tract Cancer

Gene >> S1PR2

  • 2014
  • 2015
  • 2017
Ref: Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2.
PMID: 24700501
 Ref: Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma.
PMID: 26090720
 Ref: The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice.
PMID: 28120434